Monitoring of high-intensity focused ultrasound lesion formation using decorrelation between high-speed ultrasonic images by parallel beamforming
Monitoring of high-intensity focused ultrasound lesion formation using decorrelation between high-speed ultrasonic images by parallel beamforming
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DOI：
10.7567/jjap.53.07kf10
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发表时间：
2014-07-01
影响因子：
1.5
通讯作者：
Umemura, Shin-ichiro
中科院分区：
文献类型：
--
作者：
Sasaki, Shoya;Takagi, Ryo;Umemura, Shin-ichiro
高强度聚焦超声（HIFU）是一种治疗方法，其中超声聚焦到目标组织（如癌症）进行热凝固。为了提高HIFU治疗的安全性和准确性，无创性监测热损伤形成的方法是重要的。用于此目的的潜在方法是超声成像。在这项研究中，通过并行波束形成的高速成像进行使用在HIFU曝光期间获得的超声RF信号，并计算RF帧之间的互相关系数的分布，以估计组织凝固。使用高速成像，可以准连续地照射HIFU。结果表明，在聚焦聚焦点处及其周围存在去相关现象。去相关是由组织凝固引起的RF信号的变化引起的，这通过以下事实得到证实：在焦斑处和焦斑周围的去相关像素的数量的出现和增加对应于组织凝固的开始和进展。(C)2014日本应用物理学会
High-intensity focused ultrasound (HIFU) is a type of therapeutic treatment in which ultrasound is focused to a target tissue such as cancer to be thermally coagulated. To enhance the safety and accuracy of HIFU treatment, a noninvasive method of monitoring the thermal lesion formation is important. A potential method for this purpose is ultrasound imaging. In this study, high-speed imaging by parallel beamforming was performed using ultrasound RF signals acquired during HIFU exposure, and the distribution of the cross-correlation coefficient between RF frames was calculated to estimate the tissue coagulation. Using high-speed imaging, HIFU can be irradiated quasi-continuously. The result shows that the decorrelation was observed at and around the focal spot of HIFU exposure. The decorrelation was induced by the change in RF signals owing to tissue coagulation, which was confirmed by the fact that the emergence and increase in the number of decorrelated pixels at and around the focal spot corresponded to the start and progress of tissue coagulation. (C) 2014 The Japan Society of Applied Physics