Analysis and modeling of the multisegmental coordination of shortening behavior in the medicinal leech. I. Motor output pattern.
Analysis and modeling of the multisegmental coordination of shortening behavior in the medicinal leech. I. Motor output pattern.
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药用水蛭缩短行为的多节协调分析和建模。
DOI：
10.1152/jn.1992.68.5.1683
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发表时间：
1992
影响因子：
2.5
通讯作者：
KristanJr,WB
中科院分区：
文献类型：
--
作者：
Wittenberg,G;KristanJr,WB
1.为了了解多节段动物如何协调多节段的运动活动，我们研究了药用水蛭的缩短行为，其中几个节段纵向收缩以响应中等强度的机械刺激。2.我们首先证明，负责缩短行为的神经元活动发生在半完整和孤立的神经索制备，然后其特征在于运动神经元在孤立的制剂的反应。缩短过程中的运动输出是支配背纵肌的运动神经元和支配腹纵肌的运动神经元同时兴奋。3.刺激越强，产生缩短运动输出的节段越多，最接近刺激的节段首先被招募。4.虽然缩短反应产生在几个节段附近的刺激的网站，它从来没有产生在刺激节段，在那里产生的局部弯曲电机输出模式。运动模式表明，缩短，最初被认为是一个非常简单的行为，需要至少几个节段迭代的中间神经元的参与。
1. To understand how a multisegmental animal coordinates motor activity over more than one segment, we studied shortening behavior in the medicinal leech, in which several segments contract longitudinally in response to a moderately strong mechanical stimulus. 2. We first demonstrated that the neuronal activity responsible for shortening behavior occurred in semi-intact and isolated nerve cord preparations, and then characterized the responses of motor neurons in isolated preparations. The motor output during shortening was simultaneous excitation of motor neurons innervating dorsal longitudinal muscle and of motor neurons innervating ventral longitudinal muscle. 3. The stronger the stimulus, the more segments produced the shortening motor output, with the segments nearest the stimulus recruited first. 4. Although the shortening response was produced in several segments near the site of stimulation, it was never produced in the stimulated segment, where the local bending motor output pattern was produced. The motor pattern suggests that shortening, initially considered a very simple behavior, requires the involvement of at least few segmentally iterated interneurons.