THE EFFECT OF PHOTOCOAGULATION ON THE OXYGENATION AND ULTRASTRUCTURE OF AVASCULAR RETINA
THE EFFECT OF PHOTOCOAGULATION ON THE OXYGENATION AND ULTRASTRUCTURE OF AVASCULAR RETINA
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DOI：
10.1016/0014-4835(90)90213-e
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发表时间：
1990-03-01
影响因子：
3.4
通讯作者：
HATCHELL, DL
中科院分区：
文献类型：
--
作者：
NOVACK, RL;STEFANSSON, E;HATCHELL, DL
Panretinal photocoagulation has been shown to raise preretinal oxygen tension in cats and monkeys breathing 100% oxygen. However, in normoxia, there is no significant difference between normal and photocoagulated area. This is thought to be due to autoregulatory vasoconstriction of the retinal circulation. In avascular rabbit retina, photocoagulation effects on retinal oxygenation can be studied without the influence of retinal vascular autoregulation. We meausred normoxic preretinal oxygen tension of normal and photocoagulated rabbit retina at 1, 7, 14 and 28 days after photocoagulation using polarographic oxygen electrodes. For all time points, preretinal oxygen tension of photocoagulated retina (42 .+-. 14 torr; mean .+-. S.D.) was higher than untreated retina (14.+-.10 torr; mean .+-. S.D., P < 0.001). Light and electron microscopy of lasered retina showed that the improved oxygenation corresponded to loss of mitochondria-rich inner segments of the photoreceptors.
