Effects of environment light during sleep on autonomic functions of heart rate and breathing.
Effects of environment light during sleep on autonomic functions of heart rate and breathing.
复制标题
睡眠时环境光对心率和呼吸自主功能的影响。
DOI：
10.1007/s11325-014-0951-7
复制
发表时间：
2014
期刊：
影响因子：
2.5
通讯作者：
Kimura H.
中科院分区：
文献类型：
--
作者：
Yamauchi M;Jacono FJ;Fujita Y;Kumamoto M;Yoshikawa M;Campanaro CK;Loparo KA;Strohl KP;Kimura H.
目的在对包括睡眠呼吸暂停在内的许多睡眠障碍进行评估时，发现睡眠卫生不良，包括白天睡觉或晚上开灯。本研究的目的是研究环境光是否影响自主神经控制心率、睡眠呼吸紊乱(SDB)和/或呼吸模式。研究是在家中进行的，使用3型便携式监视器结合活动记录仪进行睡眠-唤醒计时，使用随机分配的黑暗或1000lx荧光照明环境之间的交叉。在心率变异性分析中，低频功率除以高频功率(LF/HF比)，呼吸暂停低通气指数(AHI)，以及不同环境下入睡前后的呼吸模式变异。入睡前，代表呼吸不规则性的呼吸潮气量的变异系数(CV)在光环境下比暗环境下高。两种睡眠环境下入睡后潮气量的CV值均较入睡前显著降低。只有在光环境下，入睡前的呼吸模式互信息显著低于入睡后。结论光中入睡与健康志愿者的神经兴奋、SDB和静息呼吸异常有关，具有与应激源相似的效应。这些发现可能与许多与睡眠卫生不良相关的睡眠障碍有关。
PurposePoor sleep hygiene including sleeping in the daytime or with the lights on at night is discovered during the assessment of many sleep disorders including sleep apnea. The aim of this study was to investigate whether environmental light affected autonomic control of heart rate, sleep-disordered breathing (SDB), and/or breathing patterning.MethodsSeventeen non-obese healthy volunteers without witnessed snoring and apneas were recruited. Studies were performed at home using a type 3 portable monitor combined with actigraphy for sleep-wake timing, using a randomly assigned, crossover between dark, or 1,000 lx of fluorescent lighting environment. The outcomes were low-frequency power divided by high-frequency power (LF/HF ratio) in the analysis of heart rate variability, the apnea-hypopnea index (AHI), and ventilatory pattern variability before and after sleep onset between environments.ResultsThe LF/HF ratio and AHI were both significantly higher in light as compared to dark. Before sleep onset, the coefficient of variation (CV) for breath-to-breath tidal volume representing breathing irregularity tended to be higher in light than in dark environment. The CV values for tidal volume after sleep onset were significantly decreased compared with before sleep onset in both sleep environments. Mutual information of the ventilatory pattern was significantly lower before sleep onset than after sleep onset, only in the light environment.ConclusionsSleeping in the light has effects like that of a stressor as it is associated with neuroexcitation, SDB, and resting breathing irregularity in healthy volunteers. These findings may be relevant to many sleep disorders associated with poor sleep hygiene.