Ultrastructure of the Lens Epithelium in Alport’s Syndrome
Ultrastructure of the Lens Epithelium in Alport’s Syndrome
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DOI：
10.1159/000027390
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发表时间：
1998-12
期刊：
影响因子：
2.6
通讯作者：
M. Sargon;H. Çelik;C. Şener
中科院分区：
文献类型：
--
作者：
M. Sargon;H. Çelik;C. Şener
对Alport综合征晶状体上皮的超微结构进行了研究。透射电镜检查可见大量张力丝、肿胀的线粒体、扩张的高尔基复合体、扩张的粗内质网，其中一些不规则结构和髓鞘图中含有电子致密（亲锇）物质。大多数细胞具有规则形状的细胞核，只有少数不规则形状的细胞核。扫描电镜观察到晶状体上皮多态及过渡带明显变性。在过渡区之后，晶状体囊下没有上皮细胞存在，这在文献中从未报道过。
The ultrastructure of the lens epithelium in Alport’s syndrome was studied. In a transmission electron-microscopic examination, a large number of tonofilaments, swollen mitochondria, a dilated Golgi complex, a dilated rough endoplasmic reticulum with electron-dense (osmiophilic) material in some of these irregular structures and myelin figures were observed. Most of the cells had regularly shaped and only a few of them irregularly shaped nuclei. Additionally, polymorphism and marked degeneration in the transitional zone were observed in the scanning electron-microscopic examination of the lens epithelium. After the transitional zone, there were no epithelial cells present under the lens capsule, an observation that has never been reported in the literature.