DEATH RATES FROM STROKE IN ENGLAND AND WALES PREDICTED FROM PAST MATERNAL MORTALITY

DEATH RATES FROM STROKE IN ENGLAND AND WALES PREDICTED FROM PAST MATERNAL MORTALITY
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DOI:
10.1136/bmj.295.6590.83
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发表时间:
1987-07-11
影响因子:
105.7
通讯作者:
OSMOND, C
OSMOND, C
中科院分区:
医学1区
文献类型:
--
作者:
BARKER, DJP;OSMOND, C

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1911 年 4 月英格兰和威尔士孕产妇死亡率的地理差异与该时期出生的一代人中风死亡率密切相关。中风的地理分布与过去孕产妇死亡率的关系比与任何过去或现在的主要死因的关系更密切,但缺血性心脏病除外,缺血性心脏病与中风的相关系数相似。这种关系是新的证据,表明母亲的健康状况和体质不佳是其后代患中风风险的重要决定因素。
Geographical differences in maternal mortality in England and Wales during 1911-4 correlate closely with death rates from stroke in the generation born around that time. The geographical distribution of stroke is more closely related to past maternal mortality than to any leading cause of death, past or present, except ischaemic heart disease, for which correlation coefficients with stroke are similar. This relation is new evidence that poor health and physique of mothers are important determinants of the risk of stroke among their offspring.