Ancient sex-specific extension of the cytochrome c oxidase II gene in bivalves and the fidelity of doubly-uniparental inheritance
Ancient sex-specific extension of the cytochrome c oxidase II gene in bivalves and the fidelity of doubly-uniparental inheritance
复制标题
DOI：
10.1093/oxfordjournals.molbev.a004193
复制
发表时间：
2002-08-01
影响因子：
10.7
通讯作者：
Kocher, TD
中科院分区：
文献类型：
--
作者：
Curole, JP;Kocher, TD
贻贝科和蚌科的双壳贝类具有独特的线粒体DNA遗传模式，称为双单亲遗传。除了接受母系传递的mtDNA谱系外，男性还从父亲那里接受单独的mtDNA基因组。这个系统有时会受到损害，因为女性基因组偶尔会被招募到男性的遗传周期中。这些雄性化事件在贻贝科中很常见，但在蚌科中尚未报道。为了估计年龄的男性和女性谱系的蚌科，并寻找证据的雄性化，我们测序的细胞色素c氧化酶II基因和细胞色素c氧化酶I基因之间的连接。珠蚌科的雄性和雌性谱系在4.5亿年前分化。没有证据表明在此期间的雄性化，这表明有分类群的具体差异的雄性化率。巧合的是，COII基因的200个密码子的延伸存在于蚌科的雄性基因组中，可能是没有雄性化的原因。
Bivalves of the families Mytilidae and Unionidae show a unique mode of mitochondrial DNA inheritance called doubly uniparental inheritance. In addition to receiving the maternally transmitted mtDNA lineage, males receive a separate mtDNA genome from their fathers. This system is sometimes compromised, in that female genomes are occasionally recruited into the male cycle of inheritance. These masculinization events are common in the Mytilidae but have not been reported in the Unionidae. In order to estimate the age of the male and the female lineages in the Unionidae and to look for evidence of masculinization, we sequenced the junction between the cytochrome c oxidase II gene and the cytochrome c oxidase I gene. The unionid male and female lineages diverged similar to450 MYA. There is no evidence for masculinization during this period, suggesting that there are taxon-specific differences in the rate of masculinization. Coincidentally, a 200-codon extension of the COII gene is present in the male genome of the Unionidae and may be responsible for the absence of masculinization.