On the architecture of regulatory systems: evolutionary insights and implications.
On the architecture of regulatory systems: evolutionary insights and implications.
复制标题
关于监管系统的架构：进化见解和影响。
DOI：
10.1002/bies.950080608
复制
发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Dickinson,WJ
中科院分区：
文献类型：
--
作者：
Dickinson,WJ
种间比较揭示了基因表达模式的显着多样性，即使在密切相关的物种之间也是如此。组合监管机制可以促进这种多样性的演变。然而，组合网络的高度相互依赖特征将成为进化的主要限制，并可能产生许多没有直接适应价值的特征。
Interspecific comparisons reveal remarkable diversity in patterns of gene expression, even among closely related species. Combinatorial regulatory mechanisms could facilitate the evolution of this diversity. However, the high degree of interdependence characteristic of combinatorial networks would represent a major constraint on evolution and might generate many features that have no direct adaptive value.