Body size and survival in premenopausal breast cancer.
Body size and survival in premenopausal breast cancer.
复制标题
绝经前乳腺癌的体型和生存。
DOI：
10.1038/bjc.1985.104
复制
发表时间：
1985-05
影响因子：
8.8
通讯作者：
Yeates, D
中科院分区：
文献类型：
--
作者：
Greenberg, E R;Vessey, M P;McPherson, K;Doll, R;Yeates, D
对582例绝经前乳腺癌患者的生存经历进行了研究，以确定预后是否与体型或人口统计学和生殖因素有关。随访期间228例死亡，18例移民或失访。在诊断时报告的正常体重是生存率的一个强有力的预测指标，随着体重的增加，生存率有统计学上显著的降低趋势。身高和肥胖（奎特莱特指数）与生存率没有显著关系，尽管最高的女性和最肥胖的女性的情况最差。其他重要的预后特征是疾病分期和生育史（生育第一个孩子时年龄较大的妇女表现更好）。年龄在46-50岁之间的女性也更有可能存活，但随着年龄的增长没有明显的趋势。妇女的其他特征包括社会阶层、吸烟和口服避孕药的使用与生存概率没有显著相关。
The survival experience of 582 women with premenopausal breast cancer was examined to determine whether prognosis was related to body size or to demographic and reproductive factors. During the follow-up period 228 patients died and 18 emigrated or were lost to follow-up. Usual body weight, reported at the time of diagnosis, was a strong predictor of survival, with a statistically significant trend towards lower survival with increasing weight. Height and obesity (Quetelet index) were not significantly related to survival, although the tallest women and the most obese women appeared to fare worst. Other characteristics of prognostic importance were disease stage and reproductive history (women who were older when their first child was born fared better). Women aged 46-50 when diagnosed also appeared more likely to survive but no clear trend with age was evident. Other characteristics of the women including social class, cigarette use and oral contraceptive use were not significantly related to survival probability.