Anosmia in COVID-19 Associated with Injury to the Olfactory Bulbs Evident on MRI
Anosmia in COVID-19 Associated with Injury to the Olfactory Bulbs Evident on MRI
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DOI：
10.3174/ajnr.a6675
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发表时间：
2020-09-01
影响因子：
3.5
通讯作者：
Valenca, M. M.
中科院分区：
文献类型：
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作者：
Aragao, M. F. V. V.;Leal, M. C.;Valenca, M. M.
2019冠状病毒病（COVID-19）患者可能会出现嗅觉丧失或部分嗅觉丧失的症状，通常伴有味觉变化。我们报告了5例（3例嗅觉丧失）成年COVID-19患者，其中嗅球损伤被解释为MR成像上的微出血或异常增强。患者有持续性头痛（n = 4）或运动障碍（n =1）。这种嗅球损伤可能是严重急性呼吸综合征冠状病毒2引起嗅觉功能障碍的机制。
Patients with coronavirus disease 2019 (COVID-19) may have symptoms of anosmia or partial loss of the sense of smell, often accompanied by changes in taste. We report 5 cases (3 with anosmia) of adult patients with COVID-19 in whom injury to the olfactory bulbs was interpreted as microbleeding or abnormal enhancement on MR imaging. The patients had persistent headache (n = 4) or motor deficits (n =1). This olfactory bulb injury may be the mechanism by which the Severe Acute Respiratory Syndrome coronavirus 2 causes olfactory dysfunction.