Sleep in the laboratory and sleep at home: Comparisons of older insomniacs and normal sleepers
Sleep in the laboratory and sleep at home: Comparisons of older insomniacs and normal sleepers
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DOI：
10.1093/sleep/20.12.1119
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发表时间：
1997-01-01
期刊：
影响因子：
5.6
通讯作者：
Vasilas, D
中科院分区：
文献类型：
--
作者：
Edinger, JD;Fins, AI;Vasilas, D
许多实验室多导睡眠图（LPSG）研究表明，失眠症患者和匹配的无抱怨的正常对照组之间的睡眠差异不大。然而，LPSG方法在多大程度上影响这种比较的结果还有待检验。在目前的调查中，32名（16名女性，16名男性）老年（年龄大于或等于60岁）失眠症患者和32名无主诉正常睡眠者的年龄匹配和性别匹配样本进行了连续三个晚上的LPSG监测和连续三个晚上的PSG监测在他们的家中（HPSG）。通过随机分配，每组中一半的受试者首先进行LPSG，而其余受试者首先进行HPSG。使用常规评分标准对每个PSG记录进行盲法评分，并使用总睡眠时间、总睡眠时间、睡眠效率百分比、第1阶段时间、慢波睡眠时间和快速眼动潜伏期的测量结果来比较每个PSG记录地点（即实验室和家庭）内的两个受试者组。统计分析显示，正常人、睡眠者和失眠症患者在LPSG时均表现出相似的明显首夜效应（FNE）。然而，无论是所选的睡眠参数的平均值，也不反映他们的夜间变化的措施区分失眠症患者从正常睡眠者时，这些措施来自LPSG。相比之下，两个受试者组在接受HPSG时通常均无FNE。此外，失眠症患者在HPSG期间的几项睡眠测量中显示出比正常睡眠者更大的变异性。总的来说，结果表明，FNE主要是使用LPSG时的问题，HPSG可能比LPSG更敏感，可以记录正常睡眠者和失眠症患者之间的睡眠差异。需要进一步的研究来确定本文报道的结果是否与年轻人和中年人相似。
Many laboratory polysomnographic (LPSG) studies have shown only modest sleep differences between insomniacs and matched, noncomplaining normal controls. However, the extent to which LPSG methodology affects the outcome of such comparisons has yet to be tested. In the current investigation, 32 (16 females, 16 males) older (age greater than or equal to 60 years) insomniacs and an age-matched and gender-matched sample of 32 noncomplaining normal sleepers underwent three consecutive nights of LPSG monitoring and another three consecutive nights of PSG monitoring in their homes (HPSG). By random assignment, one-half of the subjects in each group underwent LPSG first, whereas the remaining subjects underwent HPSG first. Each PSG recording was blindly scored using conventional scoring criteria, and resulting measures of total sleep period, total sleep time, sleep efficiency percent, stage 1 time, slow-wave sleep time, and rapid eye movement latency were used to compare the two subject groups within each PSG recording site (i.e. lab and home). Statistical analyses showed the normals sleepers and insomniacs evidenced similar pronounced first night effects (FNEs) when undergoing LPSG. However, neither mean values of the selected sleep parameters nor measures reflecting their night-to-night variability differentiated the insomniacs from the normal sleepers when such measures were derived from LPSG. In contrast, FNEs were generally absent for both subject groups when they underwent HPSG. Moreover, the insomniacs displayed significantly greater variability in several of their sleep measures during HPSG than did the normal sleepers. Overall, results suggest FNEs are a concern mainly when using LPSG, and HPSG may be more sensitive than LPSG for documenting sleep differences between normal sleepers and insomniacs. Additional studies are needed to determine if the findings reported herein are similar for young and middle-aged adults.