Herbal supplement use by persons aged over 50 years in Britain - Frequently used herbs, concomitant use of herbs, nutritional supplements and prescription drugs, rate of informing doctors and potential for negative interactions

Herbal supplement use by persons aged over 50 years in Britain - Frequently used herbs, concomitant use of herbs, nutritional supplements and prescription drugs, rate of informing doctors and potential for negative interactions
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DOI:
10.2165/00002512-200421090-00004
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发表时间:
2004-01-01
期刊:
影响因子:
2.8
通讯作者:
Ernst, E
Ernst, E
中科院分区:
医学2区
文献类型:
--
作者:
Canter, PH;Ernst, E

文献摘要

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背景资料:英国老年人使用草药和营养补充剂的情况正在增加,尽管存在不良反应和草药与药物相互作用的风险,但医生往往不知道他们的使用情况。老年人最常使用的草药和营养补充剂的数量以及使用的具体草药提取物尚不清楚。本研究旨在确定有多少草药和营养补充剂以及哪些草药提取物是50岁以上的英国人最常使用的,并确定哪些草药药物相互作用对该年龄组的风险最大。方法:通过网站和一本流行的杂志针对50岁以上的人进行自我完成的调查。结果:受访者(n = 271)平均使用2.26种处方药和5.91种草药和营养补充剂,包括2.66种草药提取物。英国老年人使用草药经常涉及使用几种草药,经常涉及与几种营养补充剂同时使用,向医生报告的情况很少,并使老年人面临草药与药物相互作用的风险。最常用的草药和相关的风险与处方药的负面相互作用identified.Conclusions:应鼓励老年人报告使用草药和营养补充剂给他们的医生,医生应提供全面和最新的信息,潜在的草药药物相互作用。
Background: The use of herbal and nutritional supplements by older British people is increasing and despite the risks of adverse effects and negative herb-drug interactions, doctors are often not informed of their use. The number of herbal and nutritional supplements used most frequently by older people, and which particular herbal extracts are used, are unknown. This study aimed to identify how many herbal and nutritional supplements and which herbal extracts are most frequently used by British people >50 years of age, and to identify which herb-drug interactions represent the greatest risk to this age group.Method: A self-completed survey was promoted through websites and a popular magazine aimed at people >50 years of age.Results: Respondents (n = 271) used a mean of 2.26 prescription drugs and 5.91 herbal and nutritional supplements, including 2.66 herbal extracts. The use of herbal medicines by older British people frequently involves the use of several herbs, often involves concomitant use with several nutritional supplements, is poorly reported to doctors and places older people at risk of negative herb-drug interactions. The most frequently used herbs and associated risks of negative interactions with prescription drugs are identified.Conclusions: Older people should be encouraged to report the use of herbs and nutritional supplements to their doctors, and doctors should be provided with comprehensive and up-to-date information about potential herb-drug interactions.