An algorithm for use of prasugrel (effient) in patients undergoing cardiac catheterization and percutaneous coronary intervention.
An algorithm for use of prasugrel (effient) in patients undergoing cardiac catheterization and percutaneous coronary intervention.
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DOI：
10.1097/hpc.0b013e3181fe9817
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发表时间：
2010-12-01
影响因子：
--
通讯作者：
Croce, Kevin
中科院分区：
文献类型：
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作者：
Marchini, Julio;Morrow, David;Croce, Kevin
本文介绍了在布里格姆妇女医院接受心导管插入术和经皮冠状动脉介入治疗的患者中使用普拉格雷（Effient）的算法。我们的算法正在实施中，与已发表和普遍接受的护理标准一致，并基于关键试验的数据，以评估通过优化血小板抑制与普拉格雷-心肌梗死溶栓治疗改善治疗结局（TRITON-TIMI）38，该试验比较了氯吡格雷与普拉格雷在接受经皮冠状动脉介入治疗的急性冠状动脉综合征患者中的作用。重点领域包括分析普拉格雷相对于氯吡格雷在急性冠状动脉综合征患者中的获益以及普拉格雷治疗患者的适当选择。
An algorithm for use of Prasugrel (Effient) in patients undergoing cardiac catheterization and percutaneous coronary intervention at the Brigham and Women's Hospital is presented. Our algorithm, which is in the process of being implemented, is consistent with published and generally accepted standards of care and is based on data from the pivotal Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition with Prasugrel-Thrombolysis in Myocardial Infarction (TRITON-TIMI) 38, which compared clopidogrel with prasugrel in acute coronary syndrome patients undergoing percutaneous coronary intervention. Areas of focus include analysis of the benefit of prasugrel over clopidogrel in acute coronary syndrome patients and appropriate selection of patients for prasugrel treatment.