Performance evaluation of the 5-Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2-2012 Standard
Performance evaluation of the 5-Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2-2012 Standard
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DOI：
10.1002/mp.13576
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发表时间：
2019-07-01
期刊：
影响因子：
3.8
通讯作者：
Mawlawi, Osama R.
中科院分区：
文献类型：
--
作者：
Pan, Tinsu;Einstein, Samuel A.;Mawlawi, Osama R.
GE Discovery MI PET/CT系统采用模块化数字探测器设计，允许三个、四个或五个探测器块环，以5厘米的增量将轴向视场(FOV)从15厘米扩展到25厘米。这项研究调查了5环系统的性能，并将其与3环和4环系统、使用传统光电倍增管的GE Discovery IQ系统以及跨轴视野降低的GE Signa PET/MR系统进行了比较。方法在三个不同的机构对PET的性能进行评估。空间分辨率、灵敏度、计数率性能、准确度和图像质量根据国家电气制造商协会NU 2-2012标准进行测量。还测量了平均能量分辨率、平均时间分辨率和PET/CT子系统对准。使用体模来确定不同的采集时间和重建参数对图像质量的影响。以不同的扫描持续时间重建患者的回顾性扫描，以评估对图像质量的影响。结果三家机构的检测结果基本一致。在距视野中心1、10和20 cm处，采用滤波反投影算法测量的径向/切向/轴向半最大空间分辨率全宽分别为4.3/4.3/5.0 mm、5.5/4.6/6.5 mm和7.4/5.0/6.6 mm。在视野中心测量的灵敏度(20.84cps/kBq)显著高于轴向视野降低的系统。在20.8kBq/ml时，峰值噪声当量计数率为266.3 kCPS，相应的散射分数为40.2%。对峰值噪声当量计数率以下的计数损失的校正精度为3.6%。对于10 mm、13 mm、17 mm、22 mm、28 mm和37 mm的球体，图像质量模型的对比度恢复率分别为46.2%、54.3%、66.1%、71.1%、85.3%和89.3%。平均能量和时间分辨率分别为9.55%和381.7 ps。即使在采集时间短或注射活跃度低的情况下，幻影图像和患者图像也表现出极好的图像质量。结论与其他PET/CT模型相比，扩展轴位视野改善了5环GE Discovery MI扫描仪的整体PET性能。该系统有可能通过提高灵敏度来减少扫描时间或注射活动。
The GE Discovery MI PET/CT system has a modular digital detector design allowing three, four, or five detector block rings that extend the axial field-of-view (FOV) from 15 to 25 cm in 5 cm increments. This study investigated the performance of the 5-ring system and compared it to 3- and 4-ring systems; the GE Discovery IQ system that uses conventional photomultiplier tubes; and the GE Signa PET/MR system that has a reduced transaxial FOV. Methods PET performance was evaluated at three different institutions. Spatial resolution, sensitivity, counting rate performance, accuracy, and image quality were measured in accordance with National Electrical Manufacturers Association NU 2-2012 standards. The mean energy resolution, mean timing resolution, and PET/CT subsystem alignment were also measured. Phantoms were used to determine the effects of varying acquisition time and reconstruction parameters on image quality. Retrospective patient scans were reconstructed with various scan durations to evaluate the impact on image quality. Results Results from all three institutions were similar. Radial/tangential/axial full width at half maximum spatial resolution measurements using the filtered back projection algorithm were 4.3/4.3/5.0 mm, 5.5/4.6/6.5 mm, and 7.4/5.0/6.6 mm at 1, 10, and 20 cm from the center of the FOV, respectively. Measured sensitivity at the center of the FOV (20.84 cps/kBq) was significantly higher than systems with reduced axial FOV. The peak noise-equivalent counting rate was 266.3 kcps at 20.8 kBq/ml, with a corresponding scatter fraction of 40.2%. The correction accuracy for count losses up to the peak noise-equivalent counting rate was 3.6%. For the 10-, 13-, 17-, 22-, 28-, and 37-mm spheres, contrast recoveries in the image quality phantom were measured to be 46.2%, 54.3%, 66.1%, 71.1%, 85.3%, and 89.3%, respectively. The mean energy and timing resolution were 9.55% and 381.7 ps, respectively. Phantom and patient images demonstrated excellent image quality, even at short acquisition times or low injected activity. Conclusion Compared to other PET/CT models, the extended axial FOV improved the overall PET performance of the 5-ring GE Discovery MI scanner. This system offers the potential to reduce scan times or injected activities through increased sensitivity.