Prenatal Detection and Prevention of Neural Tube Defects in South Wales
Prenatal Detection and Prevention of Neural Tube Defects in South Wales
复制标题
南威尔士神经管缺陷的产前检测和预防
DOI：
10.1177/146642408610600501
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
K. Laurence
中科院分区：
文献类型：
--
作者：
K. Laurence
出生时最常见和最悲惨的畸形，虽然在欧洲大陆的发病率不到一半。这组畸形包括无脑畸形、脑膨出和脊柱裂，具有多因素病因学，其中遗传成分是多基因的，环境触发因素被认为在早期发育中引发畸形（Carter 1974）。对于已知风险增加的妇女，预防是，
commonest and most tragic malformations at birth, though on the continent of Europe the incidence is less than half. This group of malformations which comprises anencephaly, encephalocele and spina bifida have a multifactorial aetiology where the genetic component is polygenic and environmental triggers are thought to set off the malformation in early development (Carter 1974). For women known to be at increased risk, prevention is, of