Developments in the clinical understanding of osteoarthritis.

Developments in the clinical understanding of osteoarthritis.
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DOI:
10.1186/ar2531
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发表时间:
2009
影响因子:
4.9
通讯作者:
Felson DT
Felson DT
中科院分区:
医学2区
文献类型:
--
作者:
Felson DT

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随着人们认识到骨关节炎是一种整个关节的疾病,人们越来越多地关注关节环境中的特征,这些特征会导致持续的关节损伤,并可能成为疼痛的来源。本文综述了目前评估骨性关节炎进展的方法及其促进因素,可能产生疼痛的结构异常,对骨关节炎遗传学的新认识,以及新旧治疗方法的评价。
With the recognition that osteoarthritis is a disease of the whole joint, attention has focused increasingly on features in the joint environment which cause ongoing joint damage and are likely sources of pain. This article reviews current ways of assessing osteoarthritis progression and what factors potentiate it, structural abnormalities that probably produce pain, new understandings of the genetics of osteoarthritis, and evaluations of new and old treatments.
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