On-line tracking and stimulation of swimming microorganism by on-chip microrobot
On-line tracking and stimulation of swimming microorganism by on-chip microrobot
复制标题
片上微型机器人对游泳微生物的在线跟踪和刺激
DOI：
10.1109/mhs.2014.7006078
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
F. Arai
中科院分区：
文献类型：
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作者：
Belal Ahmad;T. Kawahara;T. Yasuda;F. Arai
我们提出了一种对微流控芯片内自由游动的微生物施加机械刺激的新方法。我们的方法主要是利用高速在线视觉传感器连续跟踪显微镜下游动的微生物，然后利用高速片上微执行器施加机械刺激。为了实现我们的方法，我们开发了一种能够有效观察和机械刺激游动微生物局部点的系统。本文还介绍了所开发系统的设计过程和系统控制体系结构。最后，将所开发的系统应用于实际游动草履虫的跟踪和刺激。
We have proposed a novel approach for applying mechanical stimulation to freely swimming microorganism inside of the microfluidic chip. Our approach is mainly based on continuously tracking the swimming microorganism under the microscope using a high-speed online vision sensor, and then applying the mechanical stimulation using high-speed on-chip microactuator. To realize our approach, we have developed a system that is capable of effectively observe and mechanically stimulate a local point in the swimming microorganism. The design process and the system control architecture of the developed system were also described in this paper. Finally, the developed system was applied to track and stimulate actual swimming Paramecium.