A Laser-Engraving Technique for Portable Micropneumatic Oscillators
A Laser-Engraving Technique for Portable Micropneumatic Oscillators
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DOI：
10.3390/mi9090426
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发表时间：
2018-09-01
期刊：
影响因子：
3.4
通讯作者：
Folch, Albert
中科院分区：
文献类型：
--
作者：
Balaji, Vidhya;Castro, Kurt;Folch, Albert
微流控自动化技术所处的阶段，外部硬件控制的复杂性和成本往往严重限制了微流控系统的规模和功能。自主微流体的发展旨在消除芯片外控制，以实现可扩展的系统。计时是操纵流体流动所需的数字逻辑的基本组成部分。提出了一种用3-氨基丙基三乙氧基硅烷(APTES)处理，通过表面活化将聚二甲基硅氧烷(PDMS)弹性体组装在两层激光雕刻聚甲基丙烯酸甲酯(PMMA)层之间的自驱动气动环形振荡器。所制造的振荡器的频率在3-7.5赫兹的范围内，最大恒频注射器供电操作14分钟。演示了用振荡级控制流体通道的方法。与以前的模塑或蚀刻方法相比，该制造工艺在可制造性方面有了改进，所产生的设备廉价且便携，使该技术具有更广泛的应用潜力。
Microfluidic automation technology is at a stage where the complexity and cost of external hardware control often impose severe limitations on the size and functionality of microfluidic systems. Developments in autonomous microfluidics are intended to eliminate off-chip controls to enable scalable systems. Timing is a fundamental component of the digital logic required to manipulate fluidic flow. The authors present a self-driven pneumatic ring oscillator manufactured by assembling an elastomeric sheet of polydimethylsiloxane (PDMS) between two laser-engraved polymethylmethacrylate (PMMA) layers via surface activation through treatment with 3-aminopropyltriethoxysilane (APTES). The frequency of the fabricated oscillators is in the range of 3-7.5 Hz with a maximum of 14 min constant frequency syringe-powered operation. The control of a fluidic channel with the oscillator stages is demonstrated. The fabrication process represents an improvement in manufacturability compared to previous molding or etching approaches, and the resulting devices are inexpensive and portable, making the technology potentially applicable for wider use.