Chemical treatment of machined titanium surfaces -: An in vitro study
Chemical treatment of machined titanium surfaces -: An in vitro study
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DOI：
10.1034/j.1600-0501.1999.100303.x
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发表时间：
1999-06-01
影响因子：
4.3
通讯作者：
Ericsson, I
中科院分区：
文献类型：
--
作者：
Krozer, A;Hall, J;Ericsson, I
钛牙科种植体表面上的微生物菌斑积累可导致周围组织的炎症状况。已经提出了在手术暴露后，通过氨基醇溶液在体内清洁这种污染的表面。然而，治疗后的组织愈合导致在组织-植入物界面形成纤维囊，即植入物重新整合不当。本实验旨在研究氨基醇溶液对机械加工钛表面性能的可能影响。在本实验性体外研究中使用了具有与临床使用的Branemark植入物表面相似的形貌和化学成分的钛样品，以研究氨基醇对此类表面的吸附，以及化学去除吸附的醇以恢复原始钛表面的可能性。将氨基醇溶液供应到样品表面，随后使用四种不同的方法以除去吸附的醇分子。结果表明，在水、盐溶液和5%H2O2中冲洗不能从表面去除氨基醇。然而，暴露于臭氧产生的使用商业汞灯在环境空气中导致完全去除吸附的氨基醇。结果表明，氨基醇在体外能在种植体表面形成稳定致密的膜。这种膜的存在最有可能防止在体内植入物-组织界面处发生再整合。
Microbial plaque accumulation on titanium dental implant surfaces can result in an inflammatory condition of the surrounding tissues. Cleaning of such a contaminated surface, in vivo, by means of a solution of amino-alcohol, following surgical exposure, has been proposed. However, the tissue healing following treatment resulted in formation of a fibrous capsule at the tissue-implant interface, i.e. improper implant re-integration. The present experiment was designed to investigate the possible influence of an amino-alcohol solution on machined titanium surface properties. Titanium samples with topography and chemical composition similar to the clinically used Branemark implant surfaces were used in this experimental in-vitro study to investigate the adsorption of aminoalcohol to such surfaces, and the possibilities to chemically remove the adsorbed alcohols in order to recover a pristine titanium surface. The amino-alcohol solution was supplied to the sample surfaces and four different methods were subsequently used in order to remove the adsorbed alcohol molecules. It was shown that rinsing in water, saline solution, and 5% H2O2 did not remove the amino-alcohol from the surface. However, exposure to ozone produced by using a commercial mercury lamp in ambient air resulted in complete removal of the adsorbed amino-alcohol. The results show that the amino-alcohol used forms a stable and dense film at the implant surface in vitro. Presence of such a film most likely prevents re-integration to occur at the implant-tissue interface in vivo.