HYPERVISCOSITY AND HYPOFUNCTION OF THE SEMINAL-VESICLES
HYPERVISCOSITY AND HYPOFUNCTION OF THE SEMINAL-VESICLES
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DOI：
10.3109/01485019308988370
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发表时间：
1993-01-01
期刊：
影响因子：
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通讯作者：
MAZZOLLI, AB
中科院分区：
文献类型：
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作者：
GONZALES, GF;KORTEBANI, G;MAZZOLLI, AB
这项研究旨在确定精液样本的高粘滞度是否与男性附腺功能障碍有关。它是在1989年6月至1991年6月期间连续参加不孕症诊所的男性中进行的。并根据精液样本的粘度（正常粘度或较高粘度）对男性进行分组。对229例不孕症患者的精液进行了研究。其中，155例正常粘度，74例高粘度。通过测定酸性磷酸酶来评价高粘血症对精液质量和前列腺功能的影响，通过测定校正果糖来评价精囊腺的功能。在高粘度样本中，精子活力（II-III级）、精子活力和校正果糖显著降低（p <0.05）。精液样本中高粘滞度的高患病率仅与精囊功能减退相关。事实上，36.5%的高粘血症患者的校正果糖水平降低。当仅存在前列腺功能减退或同时存在前列腺和精囊功能减退时，未观察到与高粘滞血症的相同相关性（P：NS）。进一步的分析表明，高粘度主要是在校正的精液果糖水平低于1.5 mg/mL x 10（6）spz/mL时观察到的。高粘滞血症似乎影响精子活力，并与精囊功能减退有关。
The study was designed to determine whether hyperviscosity of the semen sample is related to dysfunction of the male accessory glands. It was carried out on men who consecutively attended an infertility clinic between June 1989 and June 1991. and the men were grouped according to viscosity of semen samples (normal viscosity or higher viscosity). Semen samples from 229 infertility patients were studied. From these, 155 had normal viscosity and 74 showed hyperviscosity. The effect of hyperviscosity of semen samples on seminal quality and the function of the prostate was evaluated by acid phosphatase measurement, and the seminal vesicles by measurement of corrected fructose. Sperm motility (grades II-III), sperm vitality, and corrected fructose were significantly reduced in samples with high viscosity (p < .05). A high prevalence of hyperviscosity in semen samples was associated with only hypofunction of the seminal vesicles. In fact, 36.5% of subjects with hyperviscosity showed reduced levels of corrected fructose. The same association with hyperviscosity was not observed when only hypofunction of the prostate was present, or when hypofunction of both prostate and seminal vesicles was present (P:NS). Further analysis showed that high viscosity is observed mainly when corrected seminal fructose levels were below 1.5 mg/mL x 10(6) spz/mL. It would appear that hyperviscosity affects sperm motility and is associated with hypofunction of the seminal vesicles.