Clinical variables related to suicide attempts in schizophrenic patients: a retrospective study
Clinical variables related to suicide attempts in schizophrenic patients: a retrospective study
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DOI：
10.1016/s0920-9964(02)00164-0
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发表时间：
2003-03-01
影响因子：
4.5
通讯作者：
Mundo, E
中科院分区：
文献类型：
--
作者：
Altamura, AC;Bassetti, R;Mundo, E
在这项研究中，我们调查了慢性精神分裂症或分裂情感性障碍患者的临床或药理学变量与自杀行为之间可能的联系。103例经DSM-III-R诊断为慢性精神分裂症或分裂情感性障碍的患者进行了研究。根据一生中是否有自杀企图，将样本细分为两个子样本。回顾性收集两组患者的主要人口学及临床变量进行分析比较。企图者的尼古丁滥用或依赖率显著高于企图者（χ 2 = 3.900, df= 1, p < 0.05，优势比）。= 3.4)，有或曾经有过重度抑郁发作的可能性更大（χ 2 = 10.258, df= 1, p < 0.002, or）。= 6.5)，精神疾病未治疗持续时间（DUP）大于或等于1年的可能性更大（卡方= 6228,df= 1 p < 0.02, or）。= 12.5)，更常使用典型抗精神病药物（χ 2 = 3.979）。df = 1。p
In this study, we investigated the possible association between clinical or pharmacological variables and suicidal behavior in a sample of chronic schizophrenia or schizoaffective disorder patients. One hundred and three patients with a DSM-III-R diagnosis of chronic schizophrenia or schizoaffective disorder were studied. The sample was subdivided in two subsamples according to the presence/absence of suicidal attempts lifetime. The main demographic and clinical variables retrospectively collected were analyzed and compared between the two groups. Attempters had a significantly higher rate of nicotine abuse or dependence (chi-square = 3.900, df= 1, p < 0,05, Odds Ratio (O.R.) = 3.4), were more likely to have or have had lifetime major depressive episodes (chi-square= 10.258, df= 1, p < 0.002, OR. = 6.5), were more likely to have a duration of untreated psychosis (DUP) greater than or equal to 1 year (chi-square = 6,228, df= 1 p < 0.02, OR. = 12.5), and were more frequently prescribed typical antipsychotics (chi-square = 3.979. df= 1. p