Chemical and mutagenic patterns of airborne particulate matter collected in 17 Italian towns.
Chemical and mutagenic patterns of airborne particulate matter collected in 17 Italian towns.
复制标题
DOI：
10.1289/ehp.94102s467
复制
发表时间：
1994-10
影响因子：
10.4
通讯作者：
He J
中科院分区：
文献类型：
--
作者：
Barale R;Giromini L;Del Ry S;Barnini B;Bulleri M;Barrai I;Valerio F;Pala M;He J
利用Ames试验对1990年在意大利17个城镇收集的空气颗粒物的致突变性进行了评估。粗提物的致突变性与铅的含量相关，提示汽油车尾气对铅的直接贡献。此外，致突变性与颗粒物的量有关。与温度呈负相关。粗提物被分成酸性、碱性和中性组分。后者进一步分离为多环芳烃(PAH)、极性和非极性馏分。酸性组分和极性组分具有较高的致突变性。致突变性的平均回收率约为60%。
The mutagenicity of airborne particulate matter collected in 17 towns of Italy in 1990 was assessed using the Ames test. The mutagenicity of crude extract correlated with amount of lead, suggesting the direct contribution of gasoline car exhausts. Moreover, the mutagenicity correlated with particulate matter amounts. An inverse correlation with temperature was observed. The crude extracts were fractionated in acid, basic, and neutral fractions. The latter was further separated into polycyclic aromatic hydrocarbon (PAH), polar, and nonpolar fractions. Acid and polar fractions showed the higher mutagenicity. Average recovery of mutagenicity was about 60%.