Evidence-based novel changes in prevalence and symptom characteristics of spleen deficiency syndrome in persons of varied health status and different ages: a cross-sectional observational study.
Evidence-based novel changes in prevalence and symptom characteristics of spleen deficiency syndrome in persons of varied health status and different ages: a cross-sectional observational study.
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不同健康状况和不同年龄人群脾虚证患病率和症状特征的循证新变化：横断面观察研究
DOI：
10.1155/2014/818235
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Ding X
中科院分区：
文献类型：
--
作者：
Zhang Y;Liu Y;Li XP;Li J;Li XF;Chen L;Jiang YY;Yu H;Shi N;Han M;Ye H;Lin ZH;Chen YZ;Liu FS;Ding X
脏腑虚损是老年人重要的病理生理特征。中医衰老的核心理论是脾虚衰老（SDS），这在古今文献中都有记载。本研究的主要目标是建立一项全面的试验，评估不同年龄组中SDS的患病率、症状严重程度、频率和分布与健康状况（健康、亚健康和慢性病）的关系，以阐明脾虚在衰老过程和健康状况恶化中的作用。这项横断面观察研究在中国 4 家医院进行。研究人员对 1390 名 20-79 岁的参与者进行了访谈，他们填写了问卷，记录了症状的患病率、严重程度和频率以及其他相关信息。结果显示，SDS的患病率和症状特征随着年龄的增长和健康状况的恶化而呈现规律性。它支持了中医的观念，即脾虚是衰老、亚健康和慢性病的重要机制。及早识别SDS的预警信号和症状可能会导致亚健康和慢性病的干预甚至预防策略以及促进健康老龄化。
Deficiency of the organs is a vital pathophysiologic characteristic in the elderly. A core TCM aging theory is known as aging caused by spleen deficiency syndrome (SDS) that can be found in ancient and modern literature. The key objectives of this study were to establish a full-scale trial to evaluate the prevalence, symptom severity, frequency, and distribution of SDS in different age groups as related to health status (healthy, subhealthy, and chronic disease) to elucidate the role of spleen deficiency in the aging process and deterioration of health status. This cross-sectional observational study was conducted in 4 hospitals in China. 1390 participants aged 20–79 were interviewed by investigators who completed questionnaires recording prevalence, severity, and frequency of symptoms as well as other relevant information. The results revealed that prevalence and symptom characteristics of SDS showed regularities with increasing age and deteriorating health status. It supports the TCM concept that spleen deficiency is an important mechanism of aging, subhealth, and chronic diseases. Early recognition of the warning signs and symptoms of SDS may lead to intervention and even prevention strategies for subhealth and chronic diseases as well as promotion of healthy aging.