Novel avian leukosis viruses from domestic chicken breeds in mainland China
Novel avian leukosis viruses from domestic chicken breeds in mainland China
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来自中国大陆家养鸡种的新型禽白血病病毒
DOI：
10.1007/s00705-017-3344-y
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发表时间：
2017-07-01
影响因子：
2.7
通讯作者：
Ye, Jianqiang
中科院分区：
文献类型：
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作者：
Shao, Hongxia;Wang, Lin;Ye, Jianqiang
从我国1380份鸡种全血中分离到两种新的禽白血病病毒（ALV）。这两株ALV与ALV A-J的env（Envelope）基因完全不同，携带ALV E的LTR（long terminal repeat）基因簇。大规模的序列分析进一步表明，这些ALV（具有不同的LTR）是最近在中国和日本的家鸡品种中流行的。这些新型ALV的出现对目前的ALV根除计划提出了挑战，因此应及时和仔细地监测新型ALV，以阻止其传播和未来的进一步重组。
Two novel avian leukosis viruses (ALVs) were isolated from 1380 whole blood samples taken from domestic chicken breeds in China. The two ALVs were uniquely different from theenv(Envelope) genes of ALV A-J and carried an LTR (long terminal repeat) cluster from ALV-E. Large scale sequence analysis further showed that these ALVs (with differentenvand LTRs) were recently endemic in domestic chicken breeds in both China and Japan. The emergence of these novel ALVs is challenging the current ALV eradication program, and as such novel ALVs should be monitored in a timely and careful manner to stop their transmission and further recombination in the future.