The distribution of enkephalinlike immunoreactivity in the telencephalon of the adult and developing domestic chicken.
The distribution of enkephalinlike immunoreactivity in the telencephalon of the adult and developing domestic chicken.
复制标题
脑啡肽样免疫反应性在成年和发育中的家鸡端脑中的分布。
DOI：
10.1002/cne.902280210
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Karten,HJ
中科院分区：
文献类型：
--
作者：
Reiner,A;Davis,BM;Brecha,NC;Karten,HJ
使用免疫组织化学技术确定鸡端脑中脑啡肽样免疫反应性的分布。在古纹状体复合体中观察到脑啡肽能神经元和纤维最密集的积累，古纹状体复合体相当于哺乳动物基底神经节的鸟类。在副嗅叶 (LPO) 和古纹状体增强 (PA) 中观察到许多小脑啡肽能神经元，这两个部分是古纹状体复合体小细胞部分的两个组成部分。 LPO-PA 的脑啡肽能神经元似乎在古纹状体复合体、古纹状体原始 (PP) 的大细胞区内产生密集的脑啡肽能纤维丛。与哺乳动物基底神经节内脑啡肽的分布相比，鸟类古纹状体复合体内脑啡肽的分布支持了先前的提议，即 PP 与哺乳动物苍白球相当，PA-LPO 与尾状核壳核相当（Karten 和 Dubbeldam，'73；Kitt 和 Brauth，'81；Parent 和 Olivier，'70；Reiner 等人）等人，'83）。对鸡古纹状体复合体内脑啡肽样免疫反应性发展的观察也支持以下建议：禽类古纹状体复合体的主要组成核在哺乳动物基底神经节内具有对应物。在鸟类端脑其他部分的细胞体和纤维中也观察到脑啡肽样免疫反应性。在腹外侧端脑内，伏核、对角带核和嗅结节含有脑啡肽能细胞体和纤维，而在鸟类端脑的被称为腹侧古纹状体的部分中仅观察到脑啡肽能纤维（Kitt和Brauth，'81；Reiner等人，'83）。在端脑内侧壁内，在外侧隔核中观察到脑啡肽能纤维，而在海马旁区域观察到脑啡肽能细胞体和纤维。除上纹状体背侧外，在古纹状体复合体的背侧观察到很少的脑啡肽样免疫反应性。在背侧上纹状体内，一条脑啡肽能神经元带似乎产生了一条重叠的平行的致密脑啡肽纤维带。因此，鸟类端脑内脑啡肽样免疫反应性的分布与哺乳动物端脑中的分布表现出显着的相似性。两类脊椎动物的端脑内脑啡肽样免疫反应性的最大积累似乎出现在端脑的腹侧壁内，包括基底神经节。相比之下，脑啡肽样免疫反应性要低得多
Immunohistochemical techniques were used to determine the distribution of enkephalinlike immunoreactivity in the telencephalon of chicken. The densest accumulation of enkephalinergic neurons and fibers was observed within the paleostriatal complex, the avian equivalent of the mammalian basal ganglia. Numerous small enkephalinergic neurons were observed in both lobus parolfactorius (LPO) and the paleostriatum augmentatum (PA), the two components of the small-celled portion of the paleostriatal complex. The enkephalinergic neurons of LPO-PA appeared to give rise to a dense plexus of enkephalinergic fibers within the large-celled zone of the paleostriatal complex, the paleostriatum primitivum (PP). The distribution of enkephalin within the avian paleostriatial complex, when compared to the distribution of enkephalin within the mammalian basal ganglia, supports previous proposals that PP is comparable to the mammalian globus pallidus and that PA-LPO are comparable to the caudate-putamen (Karten and Dubbeldam,'73; Kitt and Brauth,'81; Parent and Olivier,'70; Reiner et al.,'83). Observations on the development of enkephalinlike immunoreactivity within the chicken paleostriatal complex also support the suggestion that the major component nuclei of the avian paleostriatal complex have correspondents within the mammalian basal ganglia. Enkephalinlike immunoreactivity was also observed within cell bodies and fibers in other portions of the avian telencephalon. Within the ventrolateral telencephalon, the nucleus accumbens, nucleus of the diagonal band, and tuberculum olfactorium contained enkephalinergic cell bodies and fibers while only enkephalinergic fibers were observed in the portion of the avian telencephalon that has been termed the ventral paleostriatum (Kitt and Brauth,'81; Reiner et al.,'83). Within the medial wall of the telencephalon, enkephalinergic fibers were observed in the lateral septa1 nucleus, while enkephalinergic cell bodies and fibers were observed in the parahippocampal area. Little enkephalinlike immunoreactivity was observed dorsal to the paleostriatal complex except in the hyperstriatum dorsale. Within the hyperstriatum dorsale, a band of enkephalinergic neurons appeared to give rise to an overlying parallel band of dense enkephalinergic fibers. The distribution of enkephalinlike immunoreactivity within the avian telencephalon thus shows remarkable similarity to that seen in the mammalian telencephalon. The largest accumulation of enkephalinlike immunoreactivity within the telencephalon of both vertebrate classes appears to be found within the ventrolateral wall of the telencephalon, including the basal ganglia. In comparison, much less enkephalinlike immunoreactivity