Effects of Emptying Function of Remaining Stomach on QOL in Postgastrectomy Patients
Effects of Emptying Function of Remaining Stomach on QOL in Postgastrectomy Patients
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DOI：
10.1007/s00268-011-1379-x
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发表时间：
2012-02-01
影响因子：
2.6
通讯作者：
Kameoka, Shingo
中科院分区：
文献类型：
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作者：
Hayami, Masaru;Seshimo, Akiyoshi;Kameoka, Shingo
胃切除术后患者的生活质量（QOL）下降是近年来关注的焦点。我们验证了胃排空功能如何影响生活质量。研究对象是72例连续的癌症胃切除术后患者，其中远端胃切除术（DG）后25例，近端胃切除术（PG）后18例，保留幽门胃切除术（PpG）后16例，全胃切除术（TG）后13例。使用C-13呼吸试验方法，在2小时内测量呼吸中的（CO2）-C-13水平，并确定T（max）。采用日本版SF-36量表和胃肠症状评定量表（GSRS）分析QOL和问卷结果与T（max）之间的相关性。每种手术的平均T（max）（min）分别为DG 15.4、PG 21.1、PpG 41.3和TG 10.4。T（max）在不同手术之间存在差异，但在不同调查期之间无差异。SF-36与T（max）不相关，而GSRS显示不同程序之间腹泻和总分存在差异，但调查期间之间无差异。此外，GSRS与腹痛、消化不良和总分的T（max）相关。T（max）小于21 min的患者的总评分显示出显著的症状聚集。胃切除术后患者的胃肠道症状与剩余胃的功能相关。C-13呼气试验有助于客观评估这些症状。
Attention has recently focused on decreased quality of life (QOL) that occurs in postgastrectomy patients. We verified how gastric emptying function affected QOL.Subjects were 72 consecutive patients after gastrectomy for cancer, including 25 after distal gastrectomy (DG), 18 after proximal gastrectomy (PG), 16 after pylorus-preserving gastrectomy (PpG), and 13 after total gastrectomy (TG). Using the C-13 breath test method, (CO2)-C-13 levels in breath were measured over 2 h, and T (max) was determined. Questionnaires (Japanese versions of the Short-Form 36 [SF-36] and Gastrointestinal Symptom Rating Scale [GSRS]) were used to analyze QOL and correlations between questionnaire results and T (max).Mean T (max) (min) for each procedure was 15.4 for DG, 21.1 for PG, 41.3 for PpG, and 10.4 for TG. T (max) differed between procedures, but not between survey periods. SF-36 was not correlated with T (max), whereas GSRS showed a difference in diarrhea and total score between procedures, but not between survey periods. In addition, GSRS correlated with T (max) for abdominal pain, indigestion, and total score. The total scores showed a significant symptom aggregation in patients with T (max) less than 21 min.Gastrointestinal symptoms in postgastrectomy patients were associated with the function of the remaining stomach. The C-13 breath test is useful for objectively assessing such symptoms.