NEW AND IMPROVED METHODS FOR THE RADICAL DECARBOXYLATION OF ACIDS
NEW AND IMPROVED METHODS FOR THE RADICAL DECARBOXYLATION OF ACIDS
复制标题
DOI：
10.1039/c39830000939
复制
发表时间：
1983-01-01
影响因子：
--
通讯作者：
MOTHERWELL, WB
中科院分区：
文献类型：
--
作者：
BARTON, DHR;CRICH, D;MOTHERWELL, WB
由n-羟基吡啶-2-硫酮衍生的羧酸酯在三正丁基锡烷或叔丁基硫醇处理下发生有效的自由基链脱羧成相应的正烷烃；在没有这些氢原子供体的情况下，观察到一个顺利的脱羧重排，得到了去烷基2-吡啶基硫化物。
Carboxylic acid esters derived from N-hydroxypyridine-2-thione undergo efficient radical chain decarboxylation to the corresponding nor-alkane on treatment with either tri-n-butylstannane or t-butylmercaptan; in the absence of these hydrogen atom donors a smooth decarboxylative rearrangement giving noralkyl 2-pyridyl sulphides is observed.