Neural correlates of naming actions and of naming spatial relations
Neural correlates of naming actions and of naming spatial relations
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DOI：
10.1006/nimg.2001.0775
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发表时间：
2001-06-01
期刊：
影响因子：
5.7
通讯作者：
Damasio, AR
中科院分区：
文献类型：
--
作者：
Damasio, H;Grabowski, TJ;Damasio, AR
在[0 -15]水PET实验中，10名正常受试者检索表示动作（有或没有工具）的单词，另外10名正常受试者检索表示物体之间空间关系的单词。我们的目的是验证以下假设：与命名行为和空间关系相关的显著神经活动发生在左额盖和左顶叶联合皮层，而不发生在左颞下皮层和右顶叶联合皮层。有两个控制任务，一个需要决定未知面孔的方向（我们实验室的标准控制任务），另一个需要检索表示动作和空间关系任务中使用的具体实体的单词。根据该假设，命名动作和空间关系（以面部定向任务为对照）都激活了左额叶盖；命名动作也激活了左顶叶，然而，左后IT区域同时参与命名动作和空间关系，当从这些实体进行的命名动作中减去具体实体的命名时，双侧激活了后颞枕区的MT区域，另一方面，当从命名空间关系中减去具体实体的命名时，发现左顶叶激活。当两个命名空间关系的任务相互对比时，可以看到双侧顶叶被激活，在使用抽象刺激时是右侧，在使用具体物体时是左侧。后验信息技术的活动被认为与潜意识层面的对象处理和可能的名称检索有关，(C) 2001学术出版社。
In a [O-15] water PET experiment, 10 normal subjects retrieved words denoting actions (performed with or without an implement), and another 10 normal subjects retrieved words denoting the spatial relations between objects, Our objective was to test the following hypothesis: that the salient neural activity associated with naming actions and spatial, relations occurs in left frontal operculum and left parietal association cortices, but not in the left inferotemporal cortices (IT) or in the right parietal association cortices. There were two control tasks, one requiring a decision on the orientation of unknown faces (a standard control task in our laboratory) and another requiring the retrieval of words denoting the concrete entities used in the action and spatial relations tasks. In accordance with the hypothesis, both naming actions and spatial relations (using the face orientation task as control activated the left frontal operculum; naming actions also activated the left parietal lobe, However, sectors of the left posterior IT were also engaged in both naming actions and spatial relations, When the naming of concrete entities was subtracted from the naming of actions performed with such entities, area MT in the posterior temporo-occipital region was activated bilaterally, On the other hand, when naming of the concrete entities was subtracted from the naming of spatial relations, left parietal activation was found, and when two tasks of naming spatial relations were contrasted to each other bilateral parietal activation was seen, right when abstract stimuli were used and left when concrete objects were used. The activity in posterior IT is thought to be related to object processing and possibly name retrieval at a subconscious level, (C) 2001 Academic Press.