Chronological changing patterns of clinical characteristics of Korean breast cancer patients during 10 years (1996-2006) using nationwide breast cancer registration on-line program: Biannual update

Chronological changing patterns of clinical characteristics of Korean breast cancer patients during 10 years (1996-2006) using nationwide breast cancer registration on-line program: Biannual update
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DOI:
10.1002/jso.21110
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发表时间:
2008-10-01
影响因子:
2.5
通讯作者:
Ko, Seung Sang
Ko, Seung Sang
中科院分区:
医学3区
文献类型:
--
作者:
Ko, Seung Sang

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背景资料:我们进行了这项研究,以评估韩国乳腺癌的特点和生殖因素的时间变化,从1996年至2006年。材料和方法:我们分析了102个综合医院招募的新诊断的原发性乳腺癌患者的时间变化。所有参与医院都通过全国在线登记计划提供了基本信息。结果:2006年新诊断出11,275例乳腺癌病例。2006年乳腺癌的粗发病率为46/10万(平均47.0 ± 10.8),患者的中位年龄为48岁(平均49.2 ± 10.4)(P < 0.001)。与美国和西方国家不同的是,乳腺癌的年龄分布在生命的第50个十年达到峰值;其次是第6个,第4个和第7个十年。与以前的研究结果相比,1996年,这项研究还表明,在持续增加:发病率;保乳手术;术后乳房重建;早期乳腺癌的百分比;和危险因素的患者人数。结论:我们的研究结果表明,在韩国乳腺癌的发病率将继续上升。韩国乳腺癌患者的几个特征似乎遵循西方国家的模式,但存在差异。
Background: We performed this study to evaluate the chronological changes in Korean breast cancer characteristics and reproductive factors from 1996 to 2006.Materials and Methods: We analyzed the chronological changes among newly diagnosed primary breast cancer patients recruited at 102 general hospitals. All participating hospitals provided the essential information through the nationwide on-line registration program.Results: Eleven thousand two hundred seventy five cases of breast cancer were newly diagnosed in 2006. The crude incidence rate of breast cancer of 2006 was 46 (average 47.0 +/- 10.8) among 100,000 and the patient's median age was 48 (average 49.2 +/- 10.4) years (P < 0.001). In a difference from the United States and Western countries, the age distribution of breast cancer peaked in the fifth decade of life; this was followed by the sixth, fourth, and seventh decades. Compared with the results of previous studies 1996, this study also showed a continuous increase in: the incidence; breast-conserving surgery; breast reconstruction after operation; the percentage of early breast cancer; and the number of patients with risk factors.Conclusion: Our results suggest the incidence of breast cancer in Korea will continue to rise. Several characteristics of Korean breast cancer patients seem to follow the patterns of Western countries, but differences are present.