Steroid-induced Glaucoma: An Avoidable Irreversible Blindness.
Steroid-induced Glaucoma: An Avoidable Irreversible Blindness.
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类固醇引起的青光眼：可避免的不可逆转的失明。
DOI：
10.5005/jp-journals-l0028-1226
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发表时间：
2017-05
影响因子：
--
通讯作者：
Pandav SS
中科院分区：
文献类型：
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作者：
Phulke S;Kaushik S;Kaur S;Pandav SS
类固醇是一组抗炎药物，通常用于治疗眼部和全身疾病。类固醇的不受监控的使用，特别是在滴眼液制剂中，在容易获得非处方药的情况下很常见，导致不良副作用。在眼部副作用中，白内障和青光眼是常见的。1950年报道了类固醇诱导的高眼压，当时显示长期全身使用类固醇会增加眼内压（IOP）。任何形式的类固醇长期给药伴IOP升高可引起视神经病变，导致类固醇诱导的青光眼。本文综述了类固醇性青光眼的病理生理学和流行病学，副作用的认识，以及管理原则。目的是使所有临床医生熟悉在不监测眼睛的情况下施用类固醇的潜在危险以及在患者习惯性自我处方的某些情况下不可逆失明的危险。 作者简介：王文斌，等.类固醇诱发的青光眼：避免不可逆的失明。J Curr Glaucoma Pract 2017;11（2）：67-72。
Steroids are a group of anti-inflammatory drugs, commonly used to treat ocular and systemic conditions. Unmonitored use of steroids especially in eye drop formulations is common in situations when it is easily available over-the-counter, resulting in undesirable side effects. Among the ocular side effects, cataract and glaucoma are common. Steroid-induced ocular hypertension was reported in 1950, when long-term use of systemic steroid was shown to increase the intraocular pressure (IOP). Chronic administration of steroids in any form with raised IOP can cause optic neuropathy resulting in steroid-induced glaucoma. This review describes the pathophysiology and epidemiology of steroid-induced glaucoma, recognition of side effects, and principles of management. The purpose is to familiarize all clinicians with the potential dangers of administering steroids without monitoring the eye and the dangers of irreversible blind -ness in some instances of habitual self-prescription by patients. Phulke S, Kaushik S, Kaur S, Pandav SS. Steroid-induced Glaucoma: An Avoidable Irreversible Blindness. J Curr Glaucoma Pract 2017;11(2):67-72.