Engineering biology for sustainable 1,4-butanediol synthesis.
Engineering biology for sustainable 1,4-butanediol synthesis.
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DOI:
10.1016/j.tibtech.2023.01.006
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发表时间:
2023-01
影响因子:
17.3
通讯作者:
Connor L. Trotter;G. S. Babu;Stephen Wallace
中科院分区:
文献类型:
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作者:
Connor L. Trotter;G. S. Babu;Stephen Wallace
Over the past decade, numerous approaches have been taken to replace unsustainable chemical syntheses with green biosynthetic alternatives. In a landmark paper, Yim et al. utilised anin silico-to-in vivoworkflow to enable the high-level bioproduction of the unnatural small molecule 1,4-butanediol in the bacteriumEscherichia coli.