Increasing Infectious Endocarditis Admissions Among Young People Who Inject Drugs.
Increasing Infectious Endocarditis Admissions Among Young People Who Inject Drugs.
复制标题
DOI：
10.1093/ofid/ofw157
复制
发表时间：
2016-09
影响因子：
4.2
通讯作者：
Stopka TJ
中科院分区：
文献类型：
--
作者：
Wurcel AG;Anderson JE;Chui KK;Skinner S;Knox TA;Snydman DR;Stopka TJ
注射吸毒者 (PWID) 有感染性心内膜炎 (IE) 的风险。近年来，与滥用处方阿片类药物和海洛因相关的住院率有所增加，但最近没有对注射吸毒相关 IE (IDU-IE) 住院率的调查。使用医疗保健和利用项目国家住院样本 (HCUP-NIS) 数据集，我们发现 2000 年至 2013 年间，IDU-IE 导致 IE 住院的比例从 7% 增加到 12.1%。在此期间，我们发现 15 至 34 岁人群中 IDU-IE 住院的比例显着增加（27.1%–42.0%；P < .001）和白人（40.2%–68.9%；P < .001）。在检查所有 IDU-IE 时，女性较少见（40.9%），但在 15 至 34 岁年龄组中更为常见（53%）。我们的研究结果表明，因 IDU-IE 住院的住院患者的人口统计数据正在发生变化，反映出年轻的注射吸毒者，他们比之前报道的更有可能是白人和女性。未来需要开展研究来调查与 IDU-IE 相关的风险行为和有针对性的减少伤害策略，以避免这一快速增长的年轻吸毒者群体的发病率和死亡率进一步增加。
People who inject drugs (PWID) are at risk for infective endocarditis (IE). Hospitalization rates related to misuse of prescription opioids and heroin have increased in recent years, but there are no recent investigations into rates of hospitalizations from injection drug use-related IE (IDU-IE). Using the Health Care and Utilization Project National Inpatient Sample (HCUP-NIS) dataset, we found that the proportion of IE hospitalizations from IDU-IE increased from 7% to 12.1% between 2000 and 2013. Over this time period, we detected a significant increase in the percentages of IDU-IE hospitalizations among 15- to 34-year-olds (27.1%–42.0%; P < .001) and among whites (40.2%–68.9%; P < .001). Female gender was less common when examining all the IDU-IE (40.9%), but it was more common in the 15- to 34-year-old age group (53%). Our findings suggest that the demographics of inpatients hospitalized with IDU-IE are shifting to reflect younger PWID who are more likely to be white and female than previously reported. Future studies to investigate risk behaviors associated with IDU-IE and targeted harm reduction strategies are needed to avoid further increases in morbidity and mortality in this rapidly growing population of young PWID.
登录
查看更多内容
影响因子：
168.9
作者：
Nelson, Paul K.;Mathers, Bradley M.;Cowie, Benjamin;Hagan, Holly;Des Jarlais, Don;Horyniak, Danielle;Degenhardt, Louisa
通讯作者：
Degenhardt, Louisa
影响因子：
3.7
作者：
Tookes, Hansel;Diaz, Chanelle;Doblecki-Lewis, Susanne
通讯作者：
Doblecki-Lewis, Susanne
影响因子：
2.8
作者：
Axelsson, Anna;Soholm, Helle;Iversen, Kasper
通讯作者：
Iversen, Kasper
影响因子：
4.6
作者：
Rabkin, David G.;Mokadam, Nahush A.;Aldea, Gabriel S.
通讯作者：
Aldea, Gabriel S.
影响因子：
11.8
作者：
Miro, JM;Anguera, I;Fowler, VG
通讯作者：
Fowler, VG