Role of adrenergic receptors in tumorigenesis and development of glioma
Role of adrenergic receptors in tumorigenesis and development of glioma
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DOI：
10.13294/j.aps.2020.0011
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发表时间：
2020-04-01
期刊：
影响因子：
--
通讯作者：
Hu Ping
中科院分区：
文献类型：
--
作者：
He Ye;Zhu Yu-Ge;Hu Ping
Gliomas are malignant tumors with strong invasiveness. The current treatment strategy is surgical treatment assisted by a variety of radiotherapies, chemotherapies and immunotherapies. However, the curative efficacy is limited. Adrenergic receptor (AR) is an important stress hormone receptor, which is highly involved in the regulation of the tumorigenesis and progression of various tumors by activating different downstream signal transduction pathways. Recent studies have shown that AR is dysregulated in glioma cells and tissues, and plays an important role in a series of biological behaviors such as tumorigenesis, invasion and metastasis of glioma. This article reviews the research progress of AR in the field of glioma in recent years, which provides a theoretical basis for the prevention and treatment of glioma targeting the AR.
