Exposure to Air Pollution from Traffic and Childhood Asthma Until 12 Years of Age
Exposure to Air Pollution from Traffic and Childhood Asthma Until 12 Years of Age
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DOI：
10.1097/ede.0b013e318276c1ea
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发表时间：
2013-01-01
期刊：
影响因子：
5.4
通讯作者：
Bellander, Tom
中科院分区：
文献类型：
--
作者：
Gruzieva, Olena;Bergstrom, Anna;Bellander, Tom
背景：关于长期暴露于空气污染及其对儿童呼吸道疾病影响的前瞻性数据有限。我们调查了发展的哮喘和相关症状的纵向在第一个12年的生活中的空气污染从道路交通。方法：瑞典出生队列BAMSE（儿童，过敏，环境，斯德哥尔摩，流行病学调查）包括4089名儿童进行了随访，重复的问卷调查和血液样本长达12岁。住宅、日托和学校地址、时间-活动模式、排放数据库和扩散模型被用来估计空气动力学直径的颗粒物的个人暴露
Background: There are limited prospective data on long-term exposure to air pollution and effects on childhood respiratory morbidity. We investigated the development of asthma and related symptoms longitudinally over the first 12 years of life in relation to air pollution from road traffic.Methods: The Swedish birth cohort BAMSE (Children, Allergy, Milieu, Stockholm, Epidemiological Survey) includes 4089 children who were followed up with repeated questionnaires and blood samples for up to 12 years of age. Residential, daycare, and school addresses, time-activity patterns, emission databases, and dispersion models were used to estimate individual exposure to particulate matter with aerodynamic diameter