Prefrontal cortex, cognitive control, and the registration of decision costs
Prefrontal cortex, cognitive control, and the registration of decision costs
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DOI：
10.1073/pnas.0910662107
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发表时间：
2010-04-27
影响因子：
11.1
通讯作者：
Botvinick, Matthew M.
中科院分区：
文献类型：
--
作者：
McGuire, Joseph T.;Botvinick, Matthew M.
人类的选择行为考虑了内部决策成本：人们倾向于避免以计算要求和主观努力的方式做出决策。在这里，我们调查的神经过程登记的决策成本。我们报告两个功能性MRI实验，牵连外侧前额叶皮层（LPFC）在这个功能。在实验1中，LPFC活动与自我报告的成本措施呈正相关，因为这一措施不同块的简单决定。在实验2中，LPFC活动也与基于努力的选择的个体差异相关，在具有强烈倾向的受试者中具有更高的水平，以避免认知要求的决定。这些关系持续存在，即使反应时间和错误的影响是partialleled了，链接LPFC活动的主观经验的成本，而不仅仅是响应的准确性或时间的任务。与LPFC相反，背内侧额叶皮层--一个广泛涉及性能监控的区域--与独立于公开性能的决策成本没有关系。以前的研究表明LPFC参与了执行控制。因此，我们的研究结果意味着，成本可以注册的基础上，在决策过程中招募控制机制的程度。
Human choice behavior takes account of internal decision costs: people show a tendency to avoid making decisions in ways that are computationally demanding and subjectively effortful. Here, we investigate neural processes underlying the registration of decision costs. We report two functional MRI experiments that implicate lateral prefrontal cortex (LPFC) in this function. In Experiment 1, LPFC activity correlated positively with a self-report measure of costs as this measure varied over blocks of simple decisions. In Experiment 2, LPFC activity also correlated with individual differences in effort-based choice, taking on higher levels in subjects with a strong tendency to avoid cognitively demanding decisions. These relationships persisted even when effects of reaction time and error were partialled out, linking LPFC activity to subjectively experienced costs and not merely to response accuracy or time on task. In contrast to LPFC, dorsomedial frontal cortex-an area widely implicated in performance monitoring-showed no relationship to decision costs independent of overt performance. Previous work has implicated LPFC in executive control. Our results thus imply that costs may be registered based on the degree to which control mechanisms are recruited during decision-making.