Acupuncture for Treatment of Insomnia: A Systematic Review of Randomized Controlled Trials
Acupuncture for Treatment of Insomnia: A Systematic Review of Randomized Controlled Trials
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DOI：
10.1089/acm.2009.0041
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发表时间：
2009-11-01
影响因子：
2.6
通讯作者：
Liu, Jianping
中科院分区：
文献类型：
--
作者：
Cao, Huijuan;Pan, Xingfang;Liu, Jianping
背景：针灸是中国治疗失眠的常用方法，临床研究表明，与西药相比，针刺治疗失眠可能具有良好的疗效。方法：我们纳入了针刺治疗失眠的随机对照试验。计算机检索PubMed、Cochrane图书馆(2008年第3期)、中国网络知识基础设施、中国科学期刊数据库、万方数据库。所有搜索工作于2008年12月结束。两位作者提取了数据，并独立评估了试验的质量。用Revman 5.0.17软件进行数据分析，以相对风险(RR)和平均差值(MD)表示效果估计，可信区间(CI)为95%。结果：共纳入46项随机试验，涉及3811名患者，在随机化、盲法和意向处理分析方面，试验的方法学质量总体上是良好的。Meta分析显示，针刺对匹兹堡睡眠质量指数总分的影响优于不治疗(MD-3.28，95%CI-6.10~-0.46，p=0.02；4次试验)，而真按压与假按压(MD-2.94，95%CI-5.77~-0.11，p=0.04；2次试验)相比，对匹兹堡睡眠质量指数总分有明显的改善作用。在总睡眠时间增加3小时的患者数量方面，针刺组优于药物组(RR 1.53，95%CI 1.24-1.88，p
Background: Acupuncture is commonly used in treating insomnia in China, and clinical studies have shown that acupuncture may have a beneficial effect on insomnia compared with Western medication.Methods: We included randomized controlled trials on acupuncture for insomnia. We searched PubMed, the Cochrane Library (2008 Issue 3), China Network Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), and Wan Fang Database. All searches ended in December 2008. Two authors extracted data and assessed the trials' quality independently. RevMan 5.0.17 software was used for data analysis with effect estimate presented as relative risk (RR) and mean difference (MD) with a 95% confidence interval (CI).Results: Forty-six (46) randomized trials involving 3811 patients were included, and the methodological quality of trials was generally fair in terms of randomization, blinding, and intention-to-treat analysis. Meta-analyses showed a beneficial effect of acupuncture compared with no treatment (MD -3.28, 95% CI -6.10 to -0.46, p=0.02; 4 trials) and real acupressure compared with sham acupressure (MD -2.94, 95% CI -5.77 to -0.11, p=0.04; 2 trials) on total scores of Pittsburgh Sleep Quality Index. Acupuncture was superior to medications regarding the number of patients with total sleep duration increased for >3 hours (RR 1.53, 95% CI 1.24-1.88, p