Refractive lenticule extraction (ReLEx flex) and wavefront-optimized Femto-LASIK: comparison of contrast sensitivity and high-order aberrations at 1 year
Refractive lenticule extraction (ReLEx flex) and wavefront-optimized Femto-LASIK: comparison of contrast sensitivity and high-order aberrations at 1 year
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DOI：
10.1007/s00417-012-2220-4
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发表时间：
2013-05-01
影响因子：
2.7
通讯作者：
Sekundo, Walter
中科院分区：
文献类型：
--
作者：
Gertnere, Jana;Solomatin, Igor;Sekundo, Walter
为了比较商业双眼同时手术的屈光性晶状体摘除(Relex)FLEX技术和波前优化的Femto-Lasik矫正近视和散光的1年结果，重点观察对比敏感度和高阶像差(HOA)。我们使用Carl Zeiss Meditec(CZM)VisuMax(A(R))飞秒激光系统，重复频率为200 kHz。此外，对于Femto-LASIK，使用具有非球面消融轮廓的Mel 80准分子激光(CZM)进行切削术。1年后，Relex组的平均SE为-0.23+/-0.35D，Femto-LASIK组为-0.15+/-0.27D。Relex组的中间对比敏感度在12和18CPD时分别从1.49和0.99提高到1.54和1.1。在Femto-LASIK组，术前分别为1.51和1.03，术后1年分别为1.54和1.06。术后1年，波前优化的Femto-LASIK屈光度与RELEX(A(R))屈光度相似，但准确度无显著差异。与波前优化的Femto-LASIK相比，Relex(A(R))FLEX显示出明显较少的HOA诱发性和更好的中视中期对比敏感度。
To compare 1-year results of the refractive lenticule extraction (ReLEx) flex technique performed as a commercial bilateral simultaneous procedure to a matched group of wavefront-optimized Femto-Lasik for correction of myopia and astigmatism with emphasis on contrast sensitivity and high-order aberrations (HOA).In this retrospective study 44 eyes of 22 patients with spherical equivalent (SE) of -5.13 D who underwent ReLEx were matched to 50 eyes of 25 patients with SE of -5.42 D treated by wavefront-optimized Femto-Lasik. We used Carl Zeiss Meditec (CZM) VisuMax(A (R)) femtosecond laser system with a 200 kHz repetition rate. In addition, for Femto-LASIK, MEL 80 Excimer Laser (CZM) with aspheric ablation profiles was used for ablation.At 1 year, the mean SE in the ReLEx group was -0.23 +/- 0.35 D and in the Femto-LASIK group -0.15 +/- 0.27 D. The mesopic contrast sensitivity of ReLEx treated eyes at 12 and 18 cpd improved from 1.49 and 0.99 to 1.54 and 1.1 respectively. In the Femto-LASIK group the numbers were pre-op 1.51 and 1.03, and after 1 year 1.54 and 1.06. The high-order aberrations (HOA) after ReLEx changed from 0.15 to 0.23 mu m, and after Femto-LASIK from 0.175 to 0.320 mu m (p = 0.0023).At 1 year, wavefront-optimized Femto-LASIK produced similar refractive outcomes to ReLEx(A (R)) flex with better, but non-significant accuracy. In contrast, ReLEx(A (R)) flex showed significantly less induction of HOA and better mesopic mid-term contrast sensitivity then the wavefront-optimized Femto-LASIK.