Four‐year follow‐up after uvulopalatopharyngoplasty in 50 unselected patients with obstructive sleep apnea syndrome
Four‐year follow‐up after uvulopalatopharyngoplasty in 50 unselected patients with obstructive sleep apnea syndrome
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DOI：
10.1288/00005537-199411000-00008
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发表时间：
1994-11
期刊：
影响因子：
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通讯作者：
L. Håkan Larsson;B. Carlsson‐Nordlander;E. Svanborg
中科院分区：
文献类型：
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作者：
L. Håkan Larsson;B. Carlsson‐Nordlander;E. Svanborg
研究人员对 50 名未经选择的连续阻塞性睡眠呼吸暂停综合征 (OSAS) 患者进行了研究，这些患者通过静电荷敏感床 (SCSB) 和血氧测定法（单独或与多导睡眠图结合）夜间记录呼吸运动来诊断。更新的 SCSB — 血氧测定记录评估治疗。手术后六个月，50 人中有 30 人被列为有反应者。手术后 21 个月，49 名患者中有 19 名有反应。复发患者的平均体重指数（BMI）显着增加。手术四年后，48 名患者中有 24 名有反应。反应组的术前 BMI 显着较低。 15 名无反应者需要进行后续治疗。患者的主观改善与客观结果之间不存在相关性。研究得出以下结论： 1. 未经选择的患者对 UPPP 的反应率较低。 2. 肥胖和夜间呼吸障碍指数高是负面预测因素。 3、不能仅以患者的主观恢复情况作为术后评价。 4. 通过定期随访和使用现有的治疗替代方案，大多数 OSAS 患者可以获得有效的治疗。
Fifty unselected consecutive patients with obstructive sleep apnea syndrome (OSAS) diagnosed by nocturnal recordings of respiration movements by a static charge sensitive bed (SCSB) and oximetry, alone or combined with polysomnography, were studied. Renewed SCSB—oximetry recordings evaluated treatment. Six months after surgery, 30 of 50 were classified as responders. Twenty‐one months after surgery, 19 of 49 were responders. Patients who relapsed showed a significant increase in mean body mass index (BMI). Four years after surgery, 24 of 48 patients were responders. Preoperative BMI was significantly lower in the responder group. Subsequent treatment was required in 15 nonresponders. There was no correlation between patients' subjective improvement and objective results. The study resulted in the following conclusions: 1. The responder rate to UPPP in unselected patients is low. 2. Obesity and high indices of nocturnal respiratory disturbance are negative predictors. 3. The patients' subjective recovery alone must not be used for postoperative evaluation. 4. With regular follow‐up and the use of the treatment alternatives available today, the majority of OSAS patients can receive effective treatment.