Localized malignant peritoneal mesothelioma containing rhabdoid cells

Localized malignant peritoneal mesothelioma containing rhabdoid cells
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DOI:
10.1111/j.1440-1827.1996.tb03627.x
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发表时间:
1996-05-01
影响因子:
2.2
通讯作者:
Tamai, S
Tamai, S
中科院分区:
医学4区
文献类型:
--
作者:
Matsukuma, S;Aida, S;Tamai, S

文献摘要

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一个案例是提出了本地恶性腹膜间皮瘤出现肝脏肿瘤。患者接受肿瘤切除术,但出现复发性生长,并在初次手术后10个月死亡。原发肿瘤表现为横纹肌样细胞肉瘤样特征。检查发现存在透明质酸、细胞角蛋白上皮膜抗原和波形蛋白的共免疫反应性、与小桥粒的细胞接触和胞浆内腔。这些发现支持了该肿瘤的间皮性质。复发肿瘤主要由管状乳头状增生组成。我们的结论是,目前的肿瘤是一个局部恶性间皮瘤的双相型显示主要肉瘤成分的原发肿瘤。
A case is presented of localized malignant peritoneal mesothelioma appearing as a liver neoplasm. The patient underwent tumor resection but developed a recurrent growth and died 10 months after the initial surgery. The primary tumor showed sarcomatous features with rhabdoid cells. Examination revealed the presence of hyaluronic acid, co-immunoreactivity for cytokeratin epithelial membrane antigen and vimentin, cellular contacts with small desmosomes, and intracytoplasmic lumina. These findings supported the mesothelial nature of this tumor. The recurrent tumor was composed of predominantly tubulopapillary proliferation. It was concluded that the present tumor was a localized malignant mesothelioma of a biphasic type showing a predominantly sarcomatous component in the primary tumor.