Neuromagnetic evidence for a pitch processing center in Heschl's gyrus
Neuromagnetic evidence for a pitch processing center in Heschl's gyrus
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DOI：
10.1093/cercor/13.7.765
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发表时间：
2003-07-01
期刊：
影响因子：
3.7
通讯作者：
Lütkenhöner, B
中科院分区：
文献类型：
--
作者：
Krumbholz, K;Patterson, RD;Lütkenhöner, B
已经有几次尝试使用神经磁反应的一个音调的声音（N100米）的开始，研究音高在听觉皮层的处理。不幸的是，N100m的很大一部分仅仅是对声能开始的响应，与声音是否产生音高无关。目前的研究描述了一种新的刺激范式，旨在规避能量发作的反应，从而隔离这些神经元的反应，具体参与音高处理。脑磁图的时间分辨率使我们能够表明，这种音高起始反应（POR）的潜伏期和振幅随音调的音高和音高强度而变化。空间分辨率足以表明其来源位于N100m的前方和下方，可能在Heschl回的内侧部分。
There have been several attempts to use the neuromagnetic response to the onset of a tonal sound (N100m) to study pitch processing in auditory cortex. Unfortunately, a large proportion of the N100m is simply a response to the onset of sound energy, independent of whether the sound produces a pitch. The current study describes a novel stimulus paradigm designed to circumvent the energy-onset response and thereby isolate the response of those neural elements specifically involved in pitch processing. The temporal resolution of magnetoencephalography enables us to show that the latency and amplitude of this pitch-onset response (POR) vary with the pitch and pitch strength of the tone. The spatial resolution is sufficient to show that its source lies somewhat anterior and inferior to that of the N100m, probably in the medial part of Heschl's gyrus.