Elevated lipid levels in Vietnam veterans with chronic posttraumatic stress disorder
Elevated lipid levels in Vietnam veterans with chronic posttraumatic stress disorder
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DOI：
10.1016/s0006-3223(98)00059-6
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发表时间：
1999-02-01
影响因子：
10.6
通讯作者：
Foy, D
中科院分区：
文献类型：
--
作者：
Kagan, BL;Leskin, G;Foy, D
背景：胆固醇水平升高在惊恐障碍和愤怒发作中有报道，但在重度抑郁症中没有报道。创伤后应激障碍（PTSD）无数据报道。方法：73例男性越南退伍军人慢性（PTSD）进入90天住院计划后进行血脂筛查。结果：胆固醇、低密度脂蛋白、甘油三酯升高和高密度脂蛋白降低在慢性PTSD越南退伍军人中很常见，是冠心病的重要危险因素。结论：在这一高危人群中，可能需要进行常规脂质筛查。去甲肾上腺素能系统的激活可能导致脂质水平的改变。生物精神病学1999;45：374-377（C）1999年生物精神病学学会。
Background: Elevated cholesterol levels have been reported in panic disorder and anger attacks, but not major depression. No data have been reported in posttraumatic stress disorder (PTSD).Methods: Seventy-three male Vietnam veterans with chronic (PTSD) had serum lipid screening upon entry to a 90-day inpatient program.Results: Elevated cholesterol, low-density lipoprotein, triglycerides, and reduced high-density lipoprotein, were frequent in Vietnam veterans with chronic PTSD and are significant risk factors for coronary artery disease.Conclusions: Routine lipid screening may be warranted in this at-risk population. Altered lipid levels may result from activation of the noradrenergic system. Biol Psychiatry 1999;45:374-377 (C) 1999 Society of Biological Psychiatry.