Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden
Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden
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COVID-19对儿童哮喘的影响：实践调整和疾病负担
DOI：
10.1016/j.jaip.2020.06.001
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发表时间：
2020-09-01
影响因子：
9.4
通讯作者：
Zar, Heather J.
中科院分区：
文献类型：
--
作者：
Papadopoulos, Nikolaos G.;Custovic, Adnan;Zar, Heather J.
背景技术背景：目前尚不清楚哮喘是否会影响冠状病毒疾病的易感性或严重程度2019目的：描述COVID-19大流行对儿童哮喘服务及其患者疾病负担的影响。方法：一项在线调查被发送给了真实的生活中的儿童哮喘智囊团和世界过敏组织儿童哮喘委员会的成员。调查内容包括服务提供、疾病负担以及哮喘儿童中确诊的COVID-19感染病例的临床病程等问题。结果：91名受访者完成了调查，估计照顾超过133，000名哮喘儿童。COVID-19严重影响了儿科哮喘服务：39%的患者停止了实体预约，47%的患者停止接受新患者，75%的患者就诊受到限制。咨询几乎减半，每周中位数为20（四分位数范围，10-25）例患者。大多数中心都开设了虚拟诊所和诊所。据报告，20%（10%-40%）的患者的疾病控制优于预期，而仅10%（7.5%-12.5%）的控制受到负面影响。遵守情况似乎也有所增加。在人群中仅报告了15例确诊的COVID-19病例;估计的发病率与一般儿科队列的报告没有明显差异。结论：患有哮喘的儿童似乎并没有受到COVID-19的不成比例的影响。结果甚至可能有所改善，可能是通过增加依从性和/或减少暴露。临床服务对这一流行病作出了迅速反应，限制并以虚拟会面取代了实体预约。(C)2020年美国过敏，哮喘和免疫学学会。
BACKGROUND: It is unclear whether asthma may affect susceptibility or severity of coronavirus disease 2019 (COVID-19) in children and how pediatric asthma services worldwide have responded to the pandemic.OBJECTIVE: To describe the impact of the COVID-19 pandemic on pediatric asthma services and on disease burden in their patients.METHODS: An online survey was sent to members of the Pediatric Asthma in Real Life think tank and the World Allergy Organization Pediatric Asthma Committee. It included questions on service provision, disease burden, and the clinical course of confirmed cases of COVID-19 infection among children with asthma.RESULTS: Ninety-one respondents, caring for an estimated population of more than 133,000 children with asthma, completed the survey. COVID-19 significantly impacted pediatric asthma services: 39% ceased physical appointments, 47% stopped accepting new patients, and 75% limited patients' visits. Consultations were almost halved to a median of 20 (interquartile range, 10-25) patients per week. Virtual clinics and helplines were launched in most centers. Better than expected disease control was reported in 20% (10%-40%) of patients, whereas control was negatively affected in only 10% (7.5%-12.5%). Adherence also appeared to increase. Only 15 confirmed cases of COVID-19 were reported among the population; the estimated incidence is not apparently different from the reports of general pediatric cohorts.CONCLUSIONS: Children with asthma do not appear to be disproportionately affected by COVID-19. Outcomes may even have improved, possibly through increased adherence and/or reduced exposures. Clinical services have rapidly responded to the pandemic by limiting and replacing physical appointments with virtual encounters. (C) 2020 American Academy of Allergy, Asthma & Immunology.