Recurrent aphthous stomatitis.
Recurrent aphthous stomatitis.
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DOI：
10.1016/j.cden.2013.12.002
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发表时间：
2014-04-01
影响因子：
--
通讯作者：
Greenberg, Martin S
中科院分区：
文献类型：
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作者：
Akintoye, Sunday O;Greenberg, Martin S
复发性口疮性口炎（RAS）是影响口腔黏膜最常见的溃疡性疾病。RAS主要发生在健康个体中，在免疫功能低下的个体中有不典型的临床表现。RAS的病因尚不清楚，但一些局部的、全身的、免疫的、遗传的、过敏的、营养的、微生物的因素以及免疫抑制药物被认为是RAS的病因。使用局部和全身治疗的RAS临床管理是基于症状的严重程度和病变的频率、大小和数量。治疗的目标是减少疼痛和溃疡的大小，促进愈合，减少复发的频率。
Recurrent aphthous stomatitis (RAS) is the most common ulcerative disease affecting the oral mucosa. RAS occurs mostly in healthy individuals and has an atypical clinical presentation in immunocompromised individuals. The etiology of RAS is still unknown, but several local, systemic, immunologic, genetic, allergic, nutritional, and microbial factors, as well as immunosuppressive drugs, have been proposed as causative agents. Clinical management of RAS using topical and systemic therapies is based on severity of symptoms and the frequency, size, and number of lesions. The goals of therapy are to decrease pain and ulcer size, promote healing, and decrease the frequency of recurrence.