Comparison of the INTERGROWTH-21st, National Institute of Child Health and Human Development, and WHO fetal growth standards
Comparison of the INTERGROWTH-21st, National Institute of Child Health and Human Development, and WHO fetal growth standards
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DOI：
10.1002/ijgo.12637
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发表时间：
2018-11-01
影响因子：
3.8
通讯作者：
Zhang, Jun
中科院分区：
文献类型：
--
作者：
Hua, Xiaolin;Shen, Minxue;Zhang, Jun
目的：比较intergrowth -21、美国国家儿童健康与人类发展研究所和世卫组织胎儿生长标准识别有不良围产期结局风险的胎儿的能力。方法：回顾性分析1987年11月至1991年5月在美国6个州进行的一项多中心随机对照试验（常规产前超声诊断成像）的妇女。评估各种生物特征指标（双顶骨直径、股骨长度、腹围、头围、估计胎儿体重和出生体重）的预测能力。不良结局包括严重发病率和围产期死亡。结果：共纳入9409名女性。胎龄为18-24周时测量的生物特征指标预测灵敏度不足（范围为4%-47%）。相比之下，在28-34周进行的测量预测具有统计学意义的相对风险(范围1.5-10.2；P
Objective: To compare the ability of the INTERGROWTH-21st, National Institute of Child Health and Human Development, and WHO fetal growth standards to identify fetuses at risk of adverse perinatal outcomes.Methods: A retrospective analysis was performed among women enrolled in a multicenter randomized controlled trial (Routine Antenatal Diagnostic Imaging with Ultrasound) that was conducted in six states in the USA between November 1987 and May 1991. The predictive capability of various biometric indicators (biparietal diameter, femur length, abdominal circumference, head circumference, estimated fetal weight, and birthweight) was evaluated. Adverse outcomes included severe morbidity and perinatal death.Results: There were 9409 women included. Biometric indicators measured at a gestational age of 18-24 weeks had insufficient predictive sensitivity (range, 4%-47%). By contrast, measurements taken at 28-34 weeks predicted statistically significant relative risk (range 1.5-10.2; P