Correlation of diffusion in lumbar intervertebral disks with occlusion of lumbar arteries: A study in adult volunteers
Correlation of diffusion in lumbar intervertebral disks with occlusion of lumbar arteries: A study in adult volunteers
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DOI：
10.1148/radiol.2213010134
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发表时间：
2001-12-01
期刊：
影响因子：
19.7
通讯作者：
Tervonen, O
中科院分区：
文献类型：
--
作者：
Kurunlahti, M;Kerttula, L;Tervonen, O
目的：探讨腰椎间盘弥散系数与腰椎动脉状态及退变程度的相关性。研究、材料和方法：对37名年龄在22-68岁的无症状志愿者进行腰椎矢状位T2加权成像。测量98个腰椎间盘的表观弥散系数(ADC)，并在打印前对相应的98对腰椎动脉(总动脉=196支)进行二维飞行时间磁共振血管成像。由两名放射科医生独立评估腰椎间盘退变的程度和腰动脉的状态。根据平均信号缩写：腰椎间盘中选定感兴趣区域的强度进行ADC计算。采用协方差分析方法分析DSA数字减影同一水平腰椎ADC表观弥散系数ADC值与腰椎退行性变、腰动脉状态的相关性，并用统计学软件进行组间配对分析(Scheffe后多重比较)。P值小于0.01被认为是显著的。TOF飞行时间结果：腰椎动脉状态与腰椎间盘的弥散值密切相关，ADC值随动脉退变程度的加重而降低，弥散程度不明显。共发现8个腰椎动脉状态和弥散值正常的严重退变椎间盘。结论：腰椎动脉血流受损与腰椎间盘弥散功能减退密切相关，可能在腰椎间盘退变中起重要作用。
PURPOSE: To evaluate the correlation of the diffusion values in lumbar intervertebral disks with lumbar artery status and the degree of disk degeneration. studies,MATERIALS AND METHODS: Sagittal T2-weighted images of the lumbar spine were obtained in 37 asymptomatic volunteers aged 22-68 years. The apparent diffusion coefficient (ADC) of 98 lumbar intervertebral disks was determined, and two-dimensional time-of-flight magnetic resonance angiography was performed on Published online before print the corresponding 98 lumbar artery pairs (total arteries = 196). The degree of disk degeneration and the status of lumbar arteries were evaluated independently by two radiologists. ADC calculations were performed on the basis of the average signal Abbreviations: intensities of the selected region of interest in lumbar disks. The association between ADC apparent diffusion coefficient ADC values of disks, the disk degeneration, and the status of lumbar arteries of the DSA digital subtraction same level were analyzed with analysis of covariance, and pairwise analysis between angiography groups (Scheffe post hoc multiple comparison) was performed with statistical software. P values less than.01 were considered significant. TOF time of flightRESULTS: The lumbar arterial status correlated strongly with the diffusion values of intervertebral disks, and the ADC values decreased with higher degrees of arterial degeneration and diffusion was not significant. Eight severely degenerated disks with normal lumbar artery status and diffusion values were found.CONCLUSION: Impaired flow in lumbar arteries is significantly associated with decreased diffusion in lumbar disks and may play an important role in disk degeneration.