Iron-catalyzed chemoselective cross-coupling of primary and secondary alkyl halides with arylzinc reagents
Iron-catalyzed chemoselective cross-coupling of primary and secondary alkyl halides with arylzinc reagents
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DOI：
10.1055/s-2005-871541
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发表时间：
2005-07-07
期刊：
影响因子：
2
通讯作者：
Nakamura, E
中科院分区：
文献类型：
--
作者：
Nakamura, M;Ito, S;Nakamura, E
在TMEDA的存在下，在铁催化下烷基卤化物与芳基锌试剂发生官能团相容的交偶联反应，生成多种收率良好至优异的芳香族化合物。镁盐的显著作用是促进铁催化偶联反应的关键。
Functional-group-compatible cross-coupling reaction of alkyl halides with arylzinc reagents takes place under iron catalysis in the presence of TMEDA, producing a variety of aromatic compounds in good to excellent yield. The pronounced effect of a magnesium salt was found to be the key to the promotion of the iron-catalyzed coupling reaction.