Treatment outcomes of macrolide-susceptible Mycobacterium abscessus lung disease
Treatment outcomes of macrolide-susceptible Mycobacterium abscessus lung disease
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DOI：
10.1016/j.diagmicrobio.2017
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发表时间：
2018-04-01
影响因子：
2.9
通讯作者：
Koh, Won-Jung
中科院分区：
文献类型：
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作者：
Choi, Hayoung;Jhun, Byung Woo;Koh, Won-Jung
由于对大环内酯类药物的诱导耐药性，结核分枝杆菌肺病难以治疗。然而，15%-20%的分离株对大环内酯类药物敏感。对14例大环内酯类药物敏感的M.痰培养阳性率为93%（13/14）。(C)2017爱思唯尔公司All rights reserved.
Mycobacterium abscessus lung disease is difficult to treat due to inducible resistance to macrolides. However, 15%-20% of isolates are macrolide susceptible. In 14 patients with macrolide-susceptible M. abscessus lung disease, all isolates had nonfunctional erm(41) gene, and sputum culture conversion rate was achieved in 93% (13/14) following antibiotic therapy. (C) 2017 Elsevier Inc. All rights reserved.