Interrupting Malaria Transmission: Quantifying the Impact of Interventions in Regions of Low to Moderate Transmission
Interrupting Malaria Transmission: Quantifying the Impact of Interventions in Regions of Low to Moderate Transmission
复制标题
DOI：
10.1371/journal.pone.0015149
复制
发表时间：
2010-12-02
期刊：
影响因子：
3.7
通讯作者：
Cheng, Qin
中科院分区：
文献类型：
--
作者：
Gatton, Michelle L.;Cheng, Qin
40 多个国家已消除疟疾，另外 39 个国家目前正在计划或承诺消除疟疾。迫切需要有关可用干预措施可能产生的影响以及所需时间的信息，以帮助规划资源分配。数学模型已用于研究各种干预措施的影响；当具有不同公式的多个模型产生相似的数据时，结论的强度就会增强。在这里，我们通过使用基于个体的恶性疟原虫季节性传播随机模拟模型预测，在昆虫接种率为 1,000 人的村庄中，可以中断传播并控制寄生虫重新引入
Malaria has been eliminated from over 40 countries with an additional 39 currently planning for, or committed to, elimination. Information on the likely impact of available interventions, and the required time, is urgently needed to help plan resource allocation. Mathematical modelling has been used to investigate the impact of various interventions; the strength of the conclusions is boosted when several models with differing formulation produce similar data. Here we predict by using an individual-based stochastic simulation model of seasonal Plasmodium falciparum transmission that transmission can be interrupted and parasite reintroductions controlled in villages of 1,000 individuals where the entomological inoculation rate is