MR sialography in patients with Sjögren syndrome.
MR sialography in patients with Sjögren syndrome.
复制标题
干燥综合征患者的磁共振唾液造影。
DOI：
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复制
发表时间：
1998
期刊：
影响因子：
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通讯作者：
S. Sugai
中科院分区：
文献类型：
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作者：
H. Tonami;Y. Ogawa;M. Matoba;Y. Kuginuki;H. Yokota;K. Higashi;T. Okimura;I. Yamamoto;S. Sugai
目的
本研究的目的是评价腮腺导管MR造影在干燥综合征诊断和分期中的有效性。
方法
磁共振成像进行了一个1.5 T的单位与颈部相控阵线圈。磁共振涎腺造影源图像使用重T2加权快速自旋回波序列与频谱脂肪抑制。所有图像均采用最大强度投影重建。5名健康对照者和51例确诊的干燥综合征患者（43例原发病和8例继发病）进行了MR涎腺造影检查。对所有患者进行唇腺活检，并通过病灶评分进行组织病理学分级。将MRI涎腺造影结果与唇腺活检结果进行比较，以确定该技术在干燥综合征诊断和分期中的有效性。
结果
在所有5名对照受试者中，腮腺的主管和初级分支管在MR涎腺造影图像上清晰可见。在干燥综合征患者中，腮腺内可见点状、球状、空洞状或破坏性的外观。磁共振涎腺造影的结果与唇腺活检的结果有很好的相关性。
结论
磁共振涎腺造影有可能产生诊断结果的腮腺导管的患者干燥综合征。我们的研究结果表明，这种方法将增加，并可能取代X线涎腺造影。
PURPOSE
The purpose of this study was to evaluate the effectiveness of MR sialography of the parotid gland ducts in the diagnosis and staging of Sjögren syndrome.
METHODS
MR imaging was performed on a 1.5-T unit with a neck phased-array coil. MR sialographic source images were obtained using a heavily T2-weighted fast spin-echo sequence with spectral fat suppression. All images were analyzed on the basis of maximum intensity projection reconstruction. Five healthy control subjects and 51 patients with definite Sjögren syndrome (43 with primary disease and eight with secondary disease) were examined with MR sialography. A labial gland biopsy was performed in all patients and histopathologic grading was done by means of focal scores. The findings of MR sialography were compared with the results of labial gland biopsy to determine the effectiveness of the technique in the diagnosis and staging of Sjögren syndrome.
RESULTS
In all five control subjects, the main duct and the primary branching ducts of the parotid glands were clearly visible on MR sialographic images. In patients with Sjögren syndrome, a punctate, globular, cavitary, or destructive appearance was well seen within the parotid glands. Findings obtained at MR sialography correlated well with the results of labial gland biopsy.
CONCLUSION
MR sialography has the potential to produce diagnostic findings in the parotid gland ducts of patients with Sjögren syndrome. Our results suggest that this method will augment and possibly replace X-ray sialography.
影响因子：
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作者：
FOX, RI;ROBINSON, CA;HOWELL, FV
通讯作者：
HOWELL, FV