Seroprevalence of SARS-CoV-2 antibodies among homeless people living rough, in shelters and squats: A large population-based study in France.
Seroprevalence of SARS-CoV-2 antibodies among homeless people living rough, in shelters and squats: A large population-based study in France.
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DOI：
10.1371/journal.pone.0255498
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Tinland A
中科院分区：
文献类型：
--
作者：
Loubiere S;Monfardini E;Allaria C;Mosnier M;Allibert A;Ninove L;Bosetti T;Farnarier C;Hamouda I;Auquier P;Mosnier E;Tinland A
住房过度拥挤以及卫生条件不足，导致无家可归者特别容易感染新冠病毒。我们旨在评估法国马赛全市范围内无家可归者中新冠病毒感染的血清阳性率，并考虑不同类型的住所。
一个由分布在48个不同地点（包括街道、贫民窟、非法占用的房屋、紧急或过渡性收容所以及救助中心）的外展团队组成的联盟参与了招募过程。所有参与者都同意进行免疫球蛋白M（IgM）和G（IgG）的有效快速抗体检测，并回答一份关于医疗健康状况、合并症以及既往新冠症状的问卷。还从参与者那里收集了自新冠疫情危机以来他们住房条件的信息。
2020年6月1日至8月5日，1156名无家可归的参与者被纳入研究并接受了检测。新冠病毒IgG/IgM抗体的总体血清阳性率为5.6%（95%置信区间为2.3% - 7.0%），从街头流浪者的2.2%到紧急收容所居住者的8.1%不等（P = 0.009）。大约三分之一的血清阳性参与者报告有新冠症状。与马赛的普通人群（3.6%）相比，生活在同一城市地区的无家可归者感染新冠病毒的风险显著增加（|z| = 3.65 > 1.96）。
这些研究结果强调了需要对无家可归者进行定期筛查，以防止在过度拥挤或条件不足的住所中聚集性感染。还必须提供必要的资源以保持无家可归者的健康，他们中的绝大多数都有感染新冠病毒的累积风险因素。
Overcrowded housing, as well as inadequate sanitary conditions, contribute to making homeless people particularly vulnerable to the SARS-CoV-2 infection. We aimed to assess the seroprevalence of the SARS-CoV-2 infection among people experiencing homelessness on a large city-wide scale in Marseille, France, taking into account different types of accommodation. A consortium of outreach teams in 48 different locations including streets, slums, squats, emergency or transitional shelters and drop-in centres participated in the inclusion process. All participants consented to have a validated rapid antibody assay for immunoglobulins M (IgM) and G (IgG) and to answer a questionnaire on medical health conditions, comorbidities, and previous COVID-19 symptoms. Information on their housing conditions since the COVID-19 crisis was also collected from the participants. From June 01 to August 05, 2020, 1,156 homeless participants were enrolled in the study and tested. The overall seroprevalence of SARS-CoV-2 IgG/IgM antibodies was 5.6% (95%CI 2.3–7.0), ranging from 2.2% in people living on the streets to 8.1% in people living in emergency shelters (P = 0.009). Around one third of the seropositive participants reported COVID-19 symptoms. Compared to the general population in Marseille (3.6%), the homeless population living in the same urban area experienced a significantly increased risk of SARS-CoV-2 infection (|z| = 3.65 > 1.96). These findings highlight the need for regular screening among the homeless to prevent clustering in overcrowded or inadequate accommodations. It is also necessary to provide essential resources to keep homeless people healthy, the vast majority of whom have cumulative risk factors for SARS-CoV-2 infection.
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DOI：
10.5811/westjem.2020.7.48725
发表时间：
2020-08-17
期刊：
The western journal of emergency medicine
影响因子：
--
作者：
Karb R;Samuels E;Vanjani R;Trimbur C;Napoli A
通讯作者：
Napoli A
影响因子：
12.7
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DOI：
10.1007/s11524-008-9270-2
发表时间：
2008-05-01
影响因子：
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